INTEGRATED HEALTH SCIENCES FACILITY CORE The specific objectives of the Integrated Health Sciences Facility Core (IHSFC) are to: 1) Provide the services, instrumentation and technologies needed for basic and applied environmental health research, including population-scale genomics, cell and molecular analytics, and environmental exposures and chemistry;2) Support translational research to improve exposure characterization, early detection of disease risk, biomarker discovery and development of preventive interventions for environmentally related diseases;3) Provide training in methods and technologies to present and future environmental health scientists. To achieve these goals, the IHSFC consists of the Bioanalysis, Environmental Genomics, Particles, Metals, and Organics Services. Each service provides: 1) scientific expertise and advice to Center investigators on how to best accomplish their goals;2) in-house instrumentation, exposure chambers, and technical staff for biological and environmental studies;3) access to an extraordinary menu of other analytical services in the Harvard Medical area, the Harvard-Cambridge campus, and beyond. The IHSFC supports the translational mission of the Center by the analyses performed, by maximizing efficient use of small samples from subjects in population studies, and by assisting investigators in communicating results to community groups and policymakers. Each IHSFC service also trains students, post-docs and other environmental scientists in the technologies offered. The overall benefit to the NIEHS Center is expertise and provision of analyses, assistance with translation of research and the training and development of future environmental health scientists.

Public Health Relevance

INTEGRATED HEALTH SCIENCES FACILITY CORE NARRATIVE The Integrated Health Sciences Facility Core (IHSFC) provides access to the services, instrumentation and technologies needed for basic and applied environmental health research, including population-scale genomics, cell and molecular analytics, and environmental exposures and chemistry. The IHSFC supports the translational mission of the Center directly by the analyses performed, and also indirectly by maximizing efficient use of small samples from human subjects in population studies, making it easier for the subjects and thereby making it easier to conduct the studies of human environmental health effects. Each IHSFC service also trains students, post-docs and other environmental scientists in the technologies offered, and helps provide materials for the communication of results to community groups and policy makers.

Agency
National Institute of Health (NIH)
Institute
National Institute of Environmental Health Sciences (NIEHS)
Type
Center Core Grants (P30)
Project #
2P30ES000002-51
Application #
8619188
Study Section
Environmental Health Sciences Review Committee (EHS)
Project Start
Project End
Budget Start
2014-05-09
Budget End
2015-03-31
Support Year
51
Fiscal Year
2014
Total Cost
$541,853
Indirect Cost
$206,340
Name
Harvard University
Department
Type
DUNS #
149617367
City
Boston
State
MA
Country
United States
Zip Code
02115
Li, Wenyuan; Nyhan, Marguerite M; Wilker, Elissa H et al. (2018) Recent exposure to particle radioactivity and biomarkers of oxidative stress and inflammation: The Framingham Heart Study. Environ Int 121:1210-1216
Messerlian, Carmen; Williams, Paige L; Ford, Jennifer B et al. (2018) The Environment and Reproductive Health (EARTH) Study: A Prospective Preconception Cohort. Hum Reprod Open 2018:
Lepeule, Johanna; Litonjua, Augusto A; Gasparrini, Antonio et al. (2018) Lung function association with outdoor temperature and relative humidity and its interaction with air pollution in the elderly. Environ Res 165:110-117
Draz, Mohamed Shehata; Moazeni, Maryam; Venkataramani, Manasa et al. (2018) Hybrid Paper-Plastic Microchip for Flexible and High-Performance Point-of-Care Diagnostics. Adv Funct Mater 28:
Gaskins, Audrey J; Hart, Jaime E; Mínguez-Alarcón, Lidia et al. (2018) Residential proximity to major roadways and traffic in relation to outcomes of in vitro fertilization. Environ Int 115:239-246
Specht, Aaron J; Kponee, Kale; Nkpaa, Kpobari W et al. (2018) Validation of x-ray fluorescence measurements of metals in toenail clippings against inductively coupled plasma mass spectrometry in a Nigerian population. Physiol Meas 39:085007
Nassan, Feiby L; Williams, Paige L; Gaskins, Audrey J et al. (2018) Correlation and temporal variability of urinary biomarkers of chemicals among couples: Implications for reproductive epidemiological studies. Environ Int 123:181-188
Weisskopf, Marc G; Seals, Ryan M; Webster, Thomas F (2018) Bias Amplification in Epidemiologic Analysis of Exposure to Mixtures. Environ Health Perspect 126:047003
Raz, Raanan; Kioumourtzoglou, Marianthi-Anna; Weisskopf, Marc G (2018) Live-Birth Bias and Observed Associations Between Air Pollution and Autism. Am J Epidemiol 187:2292-2296
Hart, Jaime E; Bertrand, Kimberly A; DuPre, Natalie et al. (2018) Exposure to hazardous air pollutants and risk of incident breast cancer in the nurses' health study II. Environ Health 17:28

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