INTEGRATED HEALTH SCIENCES FACILITY CORE The specific objectives of the Integrated Health Sciences Facility Core (IHSFC) are to: 1) Provide the services, instrumentation and technologies needed for basic and applied environmental health research, including population-scale genomics, cell and molecular analytics, and environmental exposures and chemistry;2) Support translational research to improve exposure characterization, early detection of disease risk, biomarker discovery and development of preventive interventions for environmentally related diseases;3) Provide training in methods and technologies to present and future environmental health scientists. To achieve these goals, the IHSFC consists of the Bioanalysis, Environmental Genomics, Particles, Metals, and Organics Services. Each service provides: 1) scientific expertise and advice to Center investigators on how to best accomplish their goals;2) in-house instrumentation, exposure chambers, and technical staff for biological and environmental studies;3) access to an extraordinary menu of other analytical services in the Harvard Medical area, the Harvard-Cambridge campus, and beyond. The IHSFC supports the translational mission of the Center by the analyses performed, by maximizing efficient use of small samples from subjects in population studies, and by assisting investigators in communicating results to community groups and policymakers. Each IHSFC service also trains students, post-docs and other environmental scientists in the technologies offered. The overall benefit to the NIEHS Center is expertise and provision of analyses, assistance with translation of research and the training and development of future environmental health scientists.

Public Health Relevance

INTEGRATED HEALTH SCIENCES FACILITY CORE NARRATIVE The Integrated Health Sciences Facility Core (IHSFC) provides access to the services, instrumentation and technologies needed for basic and applied environmental health research, including population-scale genomics, cell and molecular analytics, and environmental exposures and chemistry. The IHSFC supports the translational mission of the Center directly by the analyses performed, and also indirectly by maximizing efficient use of small samples from human subjects in population studies, making it easier for the subjects and thereby making it easier to conduct the studies of human environmental health effects. Each IHSFC service also trains students, post-docs and other environmental scientists in the technologies offered, and helps provide materials for the communication of results to community groups and policy makers.

Agency
National Institute of Health (NIH)
Institute
National Institute of Environmental Health Sciences (NIEHS)
Type
Center Core Grants (P30)
Project #
2P30ES000002-51
Application #
8619188
Study Section
Environmental Health Sciences Review Committee (EHS)
Project Start
Project End
Budget Start
2014-05-09
Budget End
2015-03-31
Support Year
51
Fiscal Year
2014
Total Cost
$541,853
Indirect Cost
$206,340
Name
Harvard University
Department
Type
DUNS #
149617367
City
Boston
State
MA
Country
United States
Zip Code
02115
Gold, Diane R; Zanobetti, Antonella (2018) Do Maternal Air Pollution Exposures Have Long-Lasting Influences on Child Blood Pressure? Hypertension 72:56-58
Lee, Alison; Leon Hsu, Hsiao-Hsien; Mathilda Chiu, Yueh-Hsiu et al. (2018) Prenatal fine particulate exposure and early childhood asthma: Effect of maternal stress and fetal sex. J Allergy Clin Immunol 141:1880-1886
Rotem, Ran S; Chodick, Gabriel; Davidovitch, Michael et al. (2018) Congenital Abnormalities of the Male Reproductive System and Risk of Autism Spectrum Disorders. Am J Epidemiol 187:656-663
Guo, Yichen; Zhang, Ruyang; Shen, Sipeng et al. (2018) DNA Methylation of LRRC3B: A Biomarker for Survival of Early-Stage Non-Small Cell Lung Cancer Patients. Cancer Epidemiol Biomarkers Prev 27:1527-1535
Kresovich, Jacob K; Bulka, Catherine M; Joyce, Brian T et al. (2018) The Inflammatory Potential of Dietary Manganese in a Cohort of Elderly Men. Biol Trace Elem Res 183:49-57
Antonelli, Joseph; Cefalu, Matthew; Palmer, Nathan et al. (2018) Doubly robust matching estimators for high dimensional confounding adjustment. Biometrics :
Chiu, Yu-Han; Bellavia, Andrea; James-Todd, Tamarra et al. (2018) Evaluating effects of prenatal exposure to phthalate mixtures on birth weight: A comparison of three statistical approaches. Environ Int 113:231-239
Sun, Ryan; Wang, Zhaoxi; Claus Henn, Birgit et al. (2018) Identification of novel loci associated with infant cognitive ability. Mol Psychiatry :
Bezold, Carla P; Banay, Rachel F; Coull, Brent A et al. (2018) The Association Between Natural Environments and Depressive Symptoms in Adolescents Living in the United States. J Adolesc Health 62:488-495
Gaffin, Jonathan M; Hauptman, Marissa; Petty, Carter R et al. (2018) Nitrogen dioxide exposure in school classrooms of inner-city children with asthma. J Allergy Clin Immunol 141:2249-2255.e2

Showing the most recent 10 out of 1142 publications