Abstract

. The Center Director has allocated a significant portion of the Center funding to cover the costs of Pilot Projects. The goals of the MIT CEHS Pilot Project Program are to achieve the following: (i) to provide initial support for new investigators to establish new lines of research in Environmental Health; (ii) to allow exploration of possible innovative new directions representing a significant departure from ongoing funded research for established investigators in Environmental Health Sciences; and (iii) to stimulate investigators from other areas of endeavor to apply their expertise to Environmental Health research. The definition of a project here is a preliminary investigation in an area of Environmental Health Science and toxicology that can be completed within 1-1.5 years and funding is available to all CEHS members and all members of the MIT faculty.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Environmental Health Sciences (NIEHS)
Type
Center Core Grants (P30)
Project #
2P30ES002109-26A1
Application #
6874793
Study Section
Environmental Health Sciences Review Committee (EHS)
Project Start
2005-04-01
Project End
2010-03-31
Budget Start
2005-04-01
Budget End
2006-03-31
Support Year
26
Fiscal Year
2005
Total Cost
$230,138
Indirect Cost

  Institution

Name
Massachusetts Institute of Technology
Department
Type
DUNS #
001425594
City
Cambridge
State
MA
Country
United States
Zip Code
02139

  Publications

Viswanathan, Srinivas R; Nogueira, Marina F; Buss, Colin G et al. (2018) Genome-scale analysis identifies paralog lethality as a vulnerability of chromosome 1p loss in cancer. Nat Genet 50:937-943
Winn, Caroline Bodi; Artim, Stephen C; Jamiel, Morgan S et al. (2018) Lung Lobe Torsion in an Adult Male Common Marmoset (Callithrix jacchus). Comp Med 68:314-318
Co, Julia Y; Cárcamo-Oyarce, Gerardo; Billings, Nicole et al. (2018) Mucins trigger dispersal of Pseudomonas aeruginosa biofilms. NPJ Biofilms Microbiomes 4:23
Keegan, Caroline; Krutzik, Stephan; Schenk, Mirjam et al. (2018) Mycobacterium tuberculosis Transfer RNA Induces IL-12p70 via Synergistic Activation of Pattern Recognition Receptors within a Cell Network. J Immunol 200:3244-3258
DiChiara, Andrew S; Li, Rasia C; Suen, Patreece H et al. (2018) A cysteine-based molecular code informs collagen C-propeptide assembly. Nat Commun 9:4206
Caron, Tyler J; Artim, Stephen C; Israelsen, William J et al. (2018) Cutaneous Dermatophilosis in a Meadow Jumping Mouse (Zapus hudsonius). Comp Med 68:25-30
Phillips, Angela M; Doud, Michael B; Gonzalez, Luna O et al. (2018) Enhanced ER proteostasis and temperature differentially impact the mutational tolerance of influenza hemagglutinin. Elife 7:
Wang, Xin; Garcia, Carlos T; Gong, Guanyu et al. (2018) Automated Online Solid-Phase Derivatization for Sensitive Quantification of Endogenous S-Nitrosoglutathione and Rapid Capture of Other Low-Molecular-Mass S-Nitrosothiols. Anal Chem 90:1967-1975
Moore, Christopher L; Papa 3rd, Louis J; Shoulders, Matthew D (2018) A Processive Protein Chimera Introduces Mutations across Defined DNA Regions In Vivo. J Am Chem Soc 140:11560-11564
Chan, Cheryl; Pham, Phuong; Dedon, Peter C et al. (2018) Lifestyle modifications: coordinating the tRNA epitranscriptome with codon bias to adapt translation during stress responses. Genome Biol 19:228

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