The primary mission of MIT's COEC program is to raise awareness and understanding of the impact of the environment on health. Awareness is the first step toward change, and therefore through educational outreach, we aim to empower cifizens to prevent environmentally induced diseases by providing them with knowledge to help inform wise choices. While COEC acfivifies reach people of all ages, it is the philosophy of this COEC to focus upon youth, a crifical at-risk portion of our community who can benefit tremendously from knowledge that will help them make better life choices. Furthermore, understanding environmental health and understanding the fundamentals of life sciences go hand-in-hand, thus providing the dual benefit of informed decision-making, and inspiration in science. Therefore, MIT COEC proposes to continue with its emphasis on youth, while at the same fime extending programmatic opportunities to teachers and health care professionals, who are best poised to disseminate valuable environmental health informafion to the community. This COEC group continues to be innovative both in terms of the conceptual materials covered, but also in terms of the pedagogical tools. Through the development of novel hands-on programs, hundreds of students have become Involved in the learning process, and thus receptive to important concepts about the environment and its impact on their health. In addifion, this past cycle, COEC reached out not only to students, but also to thousands of community members of all ages, through a variety of media, including participatory workshops, museum exhibifions, training programs, laboratory experiments, and professional videos. In close alignment with the core interests of the Center, and under strong leadership to streamline the program and opfimize its direcfion, COEC has successfully improved the public understanding of the impact of the environment on health, by connecfing the impact of exposures to basic cellular processes.
The specific aims for this next funding period are thus focused on activities that will continue to teach fundamental concepts in environmental health to community members of all ages, with emphasis on to students, teachers, health care professionals.

Agency
National Institute of Health (NIH)
Institute
National Institute of Environmental Health Sciences (NIEHS)
Type
Center Core Grants (P30)
Project #
2P30ES002109-31A1
Application #
8091649
Study Section
Environmental Health Sciences Review Committee (EHS)
Project Start
Project End
Budget Start
2011-04-15
Budget End
2012-03-31
Support Year
31
Fiscal Year
2011
Total Cost
$189,140
Indirect Cost
Name
Massachusetts Institute of Technology
Department
Type
DUNS #
001425594
City
Cambridge
State
MA
Country
United States
Zip Code
02139
Nakashige, Toshiki G; Bowman, Sarah E J; Zygiel, Emily M et al. (2018) Biophysical Examination of the Calcium-Modulated Nickel-Binding Properties of Human Calprotectin Reveals Conformational Change in the EF-Hand Domains and His3Asp Site. Biochemistry 57:4155-4164
Ganesh, B P; Hall, A; Ayyaswamy, S et al. (2018) Diacylglycerol kinase synthesized by commensal Lactobacillus reuteri diminishes protein kinase C phosphorylation and histamine-mediated signaling in the mammalian intestinal epithelium. Mucosal Immunol 11:380-393
Bauwens, Eva; Joosten, Myrthe; Taganna, Joemar et al. (2018) In silico proteomic and phylogenetic analysis of the outer membrane protein repertoire of gastric Helicobacter species. Sci Rep 8:15453
Lo, Justin H; Hao, Liangliang; Muzumdar, Mandar D et al. (2018) iRGD-guided Tumor-penetrating Nanocomplexes for Therapeutic siRNA Delivery to Pancreatic Cancer. Mol Cancer Ther 17:2377-2388
Richardson, Christopher E R; Cunden, Lisa S; Butty, Vincent L et al. (2018) A Method for Selective Depletion of Zn(II) Ions from Complex Biological Media and Evaluation of Cellular Consequences of Zn(II) Deficiency. J Am Chem Soc 140:2413-2416
Hagen, Susan J; Ang, Lay-Hong; Zheng, Yi et al. (2018) Loss of Tight Junction Protein Claudin 18 Promotes Progressive Neoplasia Development in Mouse Stomach. Gastroenterology 155:1852-1867
Viswanathan, Srinivas R; Nogueira, Marina F; Buss, Colin G et al. (2018) Genome-scale analysis identifies paralog lethality as a vulnerability of chromosome 1p loss in cancer. Nat Genet 50:937-943
Co, Julia Y; Cárcamo-Oyarce, Gerardo; Billings, Nicole et al. (2018) Mucins trigger dispersal of Pseudomonas aeruginosa biofilms. NPJ Biofilms Microbiomes 4:23
Winn, Caroline Bodi; Artim, Stephen C; Jamiel, Morgan S et al. (2018) Lung Lobe Torsion in an Adult Male Common Marmoset (Callithrix jacchus). Comp Med 68:314-318
DiChiara, Andrew S; Li, Rasia C; Suen, Patreece H et al. (2018) A cysteine-based molecular code informs collagen C-propeptide assembly. Nat Commun 9:4206

Showing the most recent 10 out of 970 publications