The Core has the following overall objectives: 1) To develop community-based studies in order to characterize exposures sustained by urban dwellers and 339 associated health effects. 2) To characterize the factors determining exposures to environmental agents as a basis for implementation and evaluation of control measures. 3) To develop resources of biological materials for studies of biomarkers of exposure, dose, and response. The Core will facilitate the translation of these biomarkers into the community for the purpose of risk characterization and prevention. 4) To develop new methodologic approaches to investigating the environment and human health. These approaches will draw on the Core 's researchers in epidemiology, biostatistics, and environmental health sciences and on resources more generally throughout the Center. 5) To work collaboratively with the Risk Sciences and Public Policy Institute to develop initiatives in risk assessment. Emphasis will be placed on development of locally relevant risk assessments. 6) To continue the development of training programs in environmental epidemiology and exposure assessment. The design and conduct of contemporary studies on the environment and health typically involve initial, multi-disciplinary discussions, an extensive design phase, vigorous data collection, and analysis using state-of-art biostatistical methods, often requiring de nova development to handle methodological challenges. For a major project, an interdisciplinary team might work together for years, as the project progresses. There will also be a need for interaction with the study community, beginning with he planning of the study and ending with the prevention of findings and imposed situation to problems. Overall, this Core is intended to facilitate and foster the development of epidemiologic studies of adverse effects and also of studies that characterize environmental exposures. Core faculty recognize the need to work together and support the concept of the core as a basis for facilitating interactions. Core meetings are a venue for elaborating a new agenda of urban health research.

Agency
National Institute of Health (NIH)
Institute
National Institute of Environmental Health Sciences (NIEHS)
Type
Center Core Grants (P30)
Project #
5P30ES003819-20
Application #
7393264
Study Section
Project Start
2007-04-01
Project End
2008-03-31
Budget Start
2007-04-01
Budget End
2008-03-31
Support Year
20
Fiscal Year
2007
Total Cost
$99,046
Indirect Cost
Name
Johns Hopkins University
Department
Type
DUNS #
001910777
City
Baltimore
State
MD
Country
United States
Zip Code
21218
Soneja, Sutyajeet I; Tielsch, James M; Khatry, Subarna K et al. (2017) Characterizing Particulate Matter Exfiltration Estimates for Alternative Cookstoves in a Village-Like Household in Rural Nepal. Environ Manage 60:797-808
Williams, D' Ann L; McCormack, Meredith C; Matsui, Elizabeth C et al. (2016) Cow allergen (Bos d2) and endotoxin concentrations are higher in the settled dust of homes proximate to industrial-scale dairy operations. J Expo Sci Environ Epidemiol 26:42-7
Bose, S; Rivera-Mariani, F; Chen, R et al. (2016) Domestic exposure to endotoxin and respiratory morbidity in former smokers with COPD. Indoor Air 26:734-42
Soneja, Sutyajeet I; Tielsch, James M; Khatry, Subarna K et al. (2016) Highlighting Uncertainty and Recommendations for Improvement of Black Carbon Biomass Fuel-Based Emission Inventories in the Indo-Gangetic Plain Region. Curr Environ Health Rep 3:73-80
Limjunyawong, Nathachit; Kearson, Alexandra; Das, Sandhya et al. (2015) Effect of point sampling density in quantifying mouse lung emphysema. Anat Rec (Hoboken) 298:531-7
Soneja, Sutyajeet I; Tielsch, James M; Curriero, Frank C et al. (2015) Determining particulate matter and black carbon exfiltration estimates for traditional cookstove use in rural Nepalese village households. Environ Sci Technol 49:5555-62
Limjunyawong, Nathachit; Fallica, Jonathan; Horton, Maureen R et al. (2015) Measurement of the pressure-volume curve in mouse lungs. J Vis Exp :52376
Heaney, Christopher D; Kmush, Brittany; Navas-Acien, Ana et al. (2015) Arsenic exposure and hepatitis E virus infection during pregnancy. Environ Res 142:273-80
Reddy, Narsa M; Potteti, Haranatha R; Vegiraju, Suryanarayana et al. (2015) PI3K-AKT Signaling via Nrf2 Protects against Hyperoxia-Induced Acute Lung Injury, but Promotes Inflammation Post-Injury Independent of Nrf2 in Mice. PLoS One 10:e0129676
Zheng, Laura Y; Umans, Jason G; Yeh, Fawn et al. (2015) The association of urine arsenic with prevalent and incident chronic kidney disease: evidence from the Strong Heart Study. Epidemiology 26:601-12

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