Abstract

The Biological Response Indicators Facility Core (BRIG) uses basic and applied research tools and methodology to help investigators identify markers of susceptibility and exposure that may be linked to disease pathogenesis. The Core uses a single administrative structure to provide services in three specific areas: DNA/RNA Analysis (A. Brooks), Flow Cytometry/lmage Analysis (D. Laskin) and Molecular Pathology (K. Reuhl and E. Richfield). The Core works closely with the Integrative Health Sciences Facility Core (IHSFC) and the Bioinformatics, Biostatistics and Computational Toxicology Facility Core on issues of experimental design. The Core provides standard operating procedures and technology training to Center investigators. The BRI Core also coordinates with studies initiated through the IHSFC and other Facility Core, and initiates sample tracking through the Center's Laboratory Information Management System (LIMS).

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Environmental Health Sciences (NIEHS)
Type
Center Core Grants (P30)
Project #
2P30ES005022-21
Application #
7790082
Study Section
Environmental Health Sciences Review Committee (EHS)
Project Start
Project End
Budget Start
2009-04-01
Budget End
2010-03-31
Support Year
21
Fiscal Year
2009
Total Cost
$357,083
Indirect Cost

  Institution

Name
University of Medicine & Dentistry of NJ
Department
Type
DUNS #
617022384
City
Piscataway
State
NJ
Country
United States
Zip Code
08854

  Publications

Fournier, S B; D'Errico, J N; Stapleton, P A (2018) Engineered nanomaterial applications in perinatal therapeutics. Pharmacol Res 130:36-43
Stapleton, P A; Hathaway, Q A; Nichols, C E et al. (2018) Maternal engineered nanomaterial inhalation during gestation alters the fetal transcriptome. Part Fibre Toxicol 15:3
Fiedler, Nancy; Weisel, Clifford; Nwankwo, Chizoba et al. (2018) Chronic Exposure to Solvents Among Construction Painters: Reductions in Exposure and Neurobehavioral Health Effects. J Occup Environ Med 60:e663-e670
Therkorn, Jennifer; Calderon, Leonardo; Cartledge, Benton et al. (2018) Inactivation of Pure Bacterial Biofilms by Impaction of Aerosolized Consumer Products Containing Nanoparticulate Metals. Environ Sci Nano 5:544-555
Lee, Heedoo; Zhang, Duo; Laskin, Debra L et al. (2018) Functional Evidence of Pulmonary Extracellular Vesicles in Infectious and Noninfectious Lung Inflammation. J Immunol 201:1500-1509
Del Giudice, Marco; Barrett, Emily S; Belsky, Jay et al. (2018) Individual differences in developmental plasticity: A role for early androgens? Psychoneuroendocrinology 90:165-173
Barrett, E S; Hoeger, K M; Sathyanarayana, S et al. (2018) Anogenital distance in newborn daughters of women with polycystic ovary syndrome indicates fetal testosterone exposure. J Dev Orig Health Dis 9:307-314
George, Blessy; Joy, Melanie S; Aleksunes, Lauren M (2018) Urinary protein biomarkers of kidney injury in patients receiving cisplatin chemotherapy. Exp Biol Med (Maywood) 243:272-282
Vail, Gwyndolin; Roepke, Troy A (2018) Membrane-initiated estrogen signaling via Gq-coupled GPCR in the central nervous system. Steroids :
Tiethof, Angela K; Richardson, Jason R; Hart, Ronald P (2018) Knockdown of Butyrylcholinesterase but Not Inhibition by Chlorpyrifos Alters Early Differentiation Mechanisms in Human Neural Stem Cells. Toxics 6:

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