The University of Iowa proposes to continue its NIEHS supported Environmental Health Sciences Research Center (EHSRC) that is dedicated to four goals: 1) to operate an interdisciplinary environmental health sciences research center with a focus on agricultural and rural environmental exposures and health effects; 2) to promote research interactions between the environmental health research units, enhance ongoing environmental health research, and facilitate initiation of new collaborative and interdisciplinary environmental health research; 3) to enhance and promote training and the development of young investigators in the environmental health sciences; and 4) to serve as a technical resource to the State of Iowa, the region, the nation, and internationally in the area of agricultural and rural environmental health. The Center includes 57 faculty from the Colleges of Public Health, Medicine and Engineering in four research cores-the Environmental Epidemiology Core, the Pulmonary Biology Core, the Occupational Health Core and the and are currently engaged in 128 environmental health research projects. The EHSRC is governed by an Administrative Core that includes a Pilot Project Grant Program that has now funded 62 grants that have resulted in over $6 million in subsequent research funding, and an excellent Center Enrichment Program. The Center has developed a very active enter Outreach and Education Core. The EHSRC supports five research facilities including the Health Registry Facility including the Health Registry Facility, the Environmental Assessment Facility, the Molecular Immunology and Cell Biology Facility, the Inhalation Toxicology Facility and the Clinical Exposure Facility. The Center will continue to focus on health outcomes highly relevant to agricultural and rural environmental health-cancer, adverse reproductive outcomes, respiratory disease, injuries and agriculturally related health outcomes-and environmental assessment and control research. The EHSRC has made very significant progress over the last four years, is now much stronger in all of its components and is prepared to continue to provide national leadership in the area of agricultural and rural environmental health research, outreach and education.

Agency
National Institute of Health (NIH)
Institute
National Institute of Environmental Health Sciences (NIEHS)
Type
Center Core Grants (P30)
Project #
2P30ES005605-11
Application #
6231329
Study Section
Environmental Health Sciences Review Committee (EHS)
Program Officer
Dearry, Allen
Project Start
1990-09-29
Project End
2004-03-31
Budget Start
2001-04-01
Budget End
2002-03-31
Support Year
11
Fiscal Year
2001
Total Cost
$1,334,074
Indirect Cost
Name
University of Iowa
Department
Public Health & Prev Medicine
Type
Schools of Public Health
DUNS #
041294109
City
Iowa City
State
IA
Country
United States
Zip Code
52242
Bao, Wei; Song, Yiqing; Bertrand, Kimberly A et al. (2018) Prepregnancy habitual intake of vitamin D from diet and supplements in relation to risk of gestational diabetes mellitus: A prospective cohort study. J Diabetes 10:373-379
Uwimana, Eric; Ruiz, Patricia; Li, Xueshu et al. (2018) HUMAN CYP2A6, CYP2B6 AND CYP2E1 ATROPSELECTIVELY METABOLIZE POLYCHLORINATED BIPHENYLS TO HYDROXYLATED METABOLITES. Environ Sci Technol :
Hofmann, Jonathan N; Shiels, Meredith S; Friesen, Melissa C et al. (2018) Industrial hog farming is associated with altered circulating immunological markers. Occup Environ Med 75:212-217
Rodriguez, Eric A; Vanle, Brigitte C; Doorn, Jonathan A et al. (2018) Hydroxylated and sulfated metabolites of commonly observed airborne polychlorinated biphenyls display selective uptake and toxicity in N27, SH-SY5Y, and HepG2 cells. Environ Toxicol Pharmacol 62:69-78
Klaren, William D; Vine, David; Vogt, Stefan et al. (2018) Spatial distribution of metals within the liver acinus and their perturbation by PCB126. Environ Sci Pollut Res Int 25:16427-16433
Das, Saikat; Oldham, Edward Davis; Lehmler, Hans-Joachim et al. (2018) Tuning the position of head groups by surfactant design in mixed micelles of cationic and carbohydrate surfactants. J Colloid Interface Sci 512:428-438
Liu, Chia-Ying; Parikh, Megha; Bluemke, David A et al. (2018) Pulmonary artery stiffness in chronic obstructive pulmonary disease (COPD) and emphysema: The Multi-Ethnic Study of Atherosclerosis (MESA) COPD Study. J Magn Reson Imaging 47:262-271
Poudel, Barun; Gurung, Prajwal (2018) Allergic asthma: RIPK2 takes the lead. J Leukoc Biol 104:441-443
Uwimana, Eric; Li, Xueshu; Lehmler, Hans-Joachim (2018) Human Liver Microsomes Atropselectively Metabolize 2,2',3,4',6-Pentachlorobiphenyl (PCB 91) to a 1,2-Shift Product as the Major Metabolite. Environ Sci Technol 52:6000-6008
Lynch, Thomas J; Anderson, Preston J; Rotti, Pavana G et al. (2018) Submucosal Gland Myoepithelial Cells Are Reserve Stem Cells That Can Regenerate Mouse Tracheal Epithelium. Cell Stem Cell 22:653-667.e5

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