Abstract

The goal of the Pulmonary Toxicology Facility Core (PTF, formerly the Inhalation Toxicology Facility) is toprovide the facilities and expertise for EHSRC investigators to enhance the productivity and quality of theirpulmonary toxicology research and to assist them in exploring new investigative areas in asthma,pulmonary biology, inhalation toxicology, or aerosol science. In addition, investigators from NIEHS-fundedEnvironmental Health Centers are supported with expertise and assays for evaluation of exposures toasthma triggers. This facility provides assistance for testing hypotheses regarding the: Pulmonary biology of asthma and other environmental lung diseases; Development and prevention of environmental lung disease; Physicochemical properties and behavior of endotoxin, allergens, bioaerosols, and other airbornetoxicants; and Performance of sampling devices commonly used by aerosol scientists and hygienists forenvironmental assessment.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Environmental Health Sciences (NIEHS)
Type
Center Core Grants (P30)
Project #
2P30ES005605-17
Application #
7239987
Study Section
Environmental Health Sciences Review Committee (EHS)
Project Start
2007-04-01
Project End
2012-03-31
Budget Start
2007-04-01
Budget End
2008-03-31
Support Year
17
Fiscal Year
2007
Total Cost
$236,286
Indirect Cost

  Institution

Name
University of Iowa
Department
Type
DUNS #
062761671
City
Iowa City
State
IA
Country
United States
Zip Code
52242

  Publications

Lee, Mi Kyeong; Carnes, Megan U; Butz, Natasha et al. (2018) Exposures Related to House Dust Microbiota in a U.S. Farming Population. Environ Health Perspect 126:067001
Rosen, Bradley H; Chanson, Marc; Gawenis, Lara R et al. (2018) Animal and model systems for studying cystic fibrosis. J Cyst Fibros 17:S28-S34
Vargas Buonfiglio, Luis G; Borcherding, Jennifer A; Frommelt, Mark et al. (2018) Airway surface liquid from smokers promotes bacterial growth and biofilm formation via iron-lactoferrin imbalance. Respir Res 19:42
Ulrich, Ethan J; Sunderland, John J; Smith, Brian J et al. (2018) Automated model-based quantitative analysis of phantoms with spherical inserts in FDG PET scans. Med Phys 45:258-276
Bao, Wei; Song, Yiqing; Bertrand, Kimberly A et al. (2018) Prepregnancy habitual intake of vitamin D from diet and supplements in relation to risk of gestational diabetes mellitus: A prospective cohort study. J Diabetes 10:373-379
Uwimana, Eric; Ruiz, Patricia; Li, Xueshu et al. (2018) HUMAN CYP2A6, CYP2B6 AND CYP2E1 ATROPSELECTIVELY METABOLIZE POLYCHLORINATED BIPHENYLS TO HYDROXYLATED METABOLITES. Environ Sci Technol :
Hofmann, Jonathan N; Shiels, Meredith S; Friesen, Melissa C et al. (2018) Industrial hog farming is associated with altered circulating immunological markers. Occup Environ Med 75:212-217
Rodriguez, Eric A; Vanle, Brigitte C; Doorn, Jonathan A et al. (2018) Hydroxylated and sulfated metabolites of commonly observed airborne polychlorinated biphenyls display selective uptake and toxicity in N27, SH-SY5Y, and HepG2 cells. Environ Toxicol Pharmacol 62:69-78
Klaren, William D; Vine, David; Vogt, Stefan et al. (2018) Spatial distribution of metals within the liver acinus and their perturbation by PCB126. Environ Sci Pollut Res Int 25:16427-16433
Das, Saikat; Oldham, Edward Davis; Lehmler, Hans-Joachim et al. (2018) Tuning the position of head groups by surfactant design in mixed micelles of cationic and carbohydrate surfactants. J Colloid Interface Sci 512:428-438

Showing the most recent 10 out of 1123 publications