The major goal of the NIEHS Center for Environmental Health Sciences at UCD is to maintain a strong program in the toxicology of agrochemicals and related xenobiotics, particularly relating to human health and the mechanistic aspects of toxicology. A team of 20 Center investigators whose interests are specifically aligned with Center goals has been assembled. Collectively these investigators are in charge of almost $12 million per year (direct costs) in research grants. The Center members include new and experienced scientists, many fields of interest, and strong histories of collaboration. To build an infrastructure which facilitates relationships within and between groups, the Center has been reorganized to form seven facility/service cores: (1) Administrative, (2) Analytical Biochemistry, (3) Cell/Tissue Culture, (4) Cellular and Molecular Imaging, (5) Field Studies (6) Functional Genomics and Molecular Biology, and (7) Primate/Animal Models. In addition, to promote focused research efforts, intellectual stimulation and synergistic interactions, five research cores have been formed: (1) Epidemiology, (2) Molecular Neurotoxicology, (3) Reproductive and Developmental Toxicology, (4) Respiratory Toxicology, and our newest core, (5) Toxicogenomics. The composition of these cores changed to provide flexibility to the Center?s research directions. The Pilot Projects Program is used to bring in new investigators and research ideas. An Affiliate Scientist category was developed to recognize interactions with UCD faculty through a less formal mechanism than full membership, and 11 new Affiliate members were appointed. The new COEP has been carefully guided by the Center Director, and under the leadership of the new coordinator, Rebecca Morrison, the COEP Mini-Grants Program has been an effective program to identify new ideas. From those ideas came a successful long-term program that currently supports four outreach programs for agricultural workers, three K-12 programs, and an alumni/corporate outreach program. In addition, during the current project period, the COEP conducted a national symposium on aging and a town-hall meeting, and sponsored the International Congress on Ecosystem Health in 1999 and the Dioxin 2000 Twentieth International Symposium on Halogenated Environmental Organic Pollutants and POPS. The COEP also serves as an Environmental Health Information Center for the public, answering questions via phone and e-mail, and disseminating information via websites, list servers, newsletters, and annual community events attended by approximately 1,000 people/year. The CEHS program is reviewed annually by the External Advisory Committee consisting of experts in this area of science, the Internal Advisory Committee consisting of eminent scientists with administrative experience at UCD, and the Executive Committee composed of CEHS faculty. The UCD has made a strong commitment of support (approximately 40%/year) by providing salaries and benefits for all Center investigators, providing space, and purchasing equipment for the CEHS.

Agency
National Institute of Health (NIH)
Institute
National Institute of Environmental Health Sciences (NIEHS)
Type
Center Core Grants (P30)
Project #
2P30ES005707-11
Application #
6421967
Study Section
Environmental Health Sciences Review Committee (EHS)
Program Officer
Dearry, Allen
Project Start
1992-09-30
Project End
2007-03-31
Budget Start
2002-04-22
Budget End
2003-03-31
Support Year
11
Fiscal Year
2002
Total Cost
$1,436,512
Indirect Cost
Name
University of California Davis
Department
Public Health & Prev Medicine
Type
Schools of Earth Sciences/Natur
DUNS #
094878337
City
Davis
State
CA
Country
United States
Zip Code
95618
Sirish, Padmini; Li, Ning; Timofeyev, Valeriy et al. (2016) Molecular Mechanisms and New Treatment Paradigm for Atrial Fibrillation. Circ Arrhythm Electrophysiol 9:
Gold, Ellen B; Blount, Benjamin C; O'Neill Rasor, Marianne et al. (2013) Thyroid hormones and thyroid disease in relation to perchlorate dose and residence near a superfund site. J Expo Sci Environ Epidemiol 23:399-408
Xiao, Hong; McCurdy, Stephen A; Stoecklin-Marois, Maria T et al. (2013) Agricultural work and chronic musculoskeletal pain among Latino farm workers: the MICASA study. Am J Ind Med 56:216-25
Moran, Francisco M; Chen, Jiangang; Gee, Nancy A et al. (2013) Dehydroepiandrosterone sulfate levels reflect endogenous luteinizing hormone production and response to human chorionic gonadotropin challenge in older female macaque (Macaca fascicularis). Menopause 20:329-35
Kim, In-Hae; Nishi, Kosuke; Kasagami, Takeo et al. (2012) Biologically active ester derivatives as potent inhibitors of the soluble epoxide hydrolase. Bioorg Med Chem Lett 22:5889-92
Plopper, C G; Joad, J P; Miller, L A et al. (2012) Lung effects of inhaled corticosteroids in a rhesus monkey model of childhood asthma. Clin Exp Allergy 42:1104-18
Tsuji, Mayumi; Kawamoto, Toshihiro; Koriyama, Chihaya et al. (2012) IL-22 mRNA expression in blood samples as a useful biomarker for assessing the adverse health effects of PCBs on allergic children. Int J Environ Res Public Health 9:4321-32
Chan, Jackie K W; Fanucchi, Michelle V; Anderson, Donald S et al. (2011) Susceptibility to inhaled flame-generated ultrafine soot in neonatal and adult rat lungs. Toxicol Sci 124:472-86
Tabares-da Rosa, Sofia; Rossotti, Martin; Carleiza, Carmen et al. (2011) Competitive selection from single domain antibody libraries allows isolation of high-affinity antihapten antibodies that are not favored in the llama immune response. Anal Chem 83:7213-20
Sciullo, Eric M; Vogel, Christoph F; Wu, Dalei et al. (2010) Effects of selected food phytochemicals in reducing the toxic actions of TCDD and p,p'-DDT in U937 macrophages. Arch Toxicol 84:957-66

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