The goals of this Research Core are to investigate the molecular mechanisms by which genotoxic environmental agents are metabolized to toxic intermediates; how genotoxic agents damage DNA; how DNA damage leads to mutation; how some cellular responses function to prevent mutagenesis (e.g., DNA repair and cell cycle arrest). Each of these aims is said to fit within the goals of the center as a whole in that they can be related to the """"""""impact of genetic diversity on the response of the individual to toxic environmental agents.""""""""

Agency
National Institute of Health (NIH)
Institute
National Institute of Environmental Health Sciences (NIEHS)
Type
Center Core Grants (P30)
Project #
2P30ES006096-06A1
Application #
6239649
Study Section
Project Start
1997-09-30
Project End
1998-03-31
Budget Start
1996-10-01
Budget End
1997-09-30
Support Year
6
Fiscal Year
1997
Total Cost
Indirect Cost
Name
University of Cincinnati
Department
Type
DUNS #
City
Cincinnati
State
OH
Country
United States
Zip Code
45221
Kim, Stephani; Xu, Xijin; Zhang, Yuling et al. (2018) Metal concentrations in pregnant women and neonates from informal electronic waste recycling. J Expo Sci Environ Epidemiol :
Chen, Jing; Gálvez-Peralta, Marina; Zhang, Xiang et al. (2018) In utero gene expression in the Slc39a8(neo/neo) knockdown mouse. Sci Rep 8:10703
Abdel-Hameed, Enass A; Rouster, Susan D; Boyce, Ceejay L et al. (2018) Ultra-Deep Genomic Sequencing of HCV NS5A Resistance-Associated Substitutions in HCV/HIV Coinfected Patients. Dig Dis Sci 63:645-652
Dobraca, Dina; Lum, Raymond; Sjödin, Andreas et al. (2018) Urinary biomarkers of polycyclic aromatic hydrocarbons in pre- and peri-pubertal girls in Northern California: Predictors of exposure and temporal variability. Environ Res 165:46-54
Miller, Marian L; Porollo, Aleksey; Wert, Susan (2018) Ultrastructure of Highly Ordered Granules in Alveolar Type II Cells in Several Species. Anat Rec (Hoboken) :
Ren, Sheng; Haynes, Erin; Hall, Eric et al. (2018) Periconception Exposure to Air Pollution and Risk of Congenital Malformations. J Pediatr 193:76-84.e6
Bhattacharya, Sukanta S; Yadav, Jagjit S (2018) Microbial P450 Enzymes in Bioremediation and Drug Discovery: Emerging Potentials and Challenges. Curr Protein Pept Sci 19:75-86
VonHandorf, Andrew; Sánchez-Martín, Francisco Javier; Biesiada, Jacek et al. (2018) Chromium disrupts chromatin organization and CTCF access to its cognate sites in promoters of differentially expressed genes. Epigenetics 13:363-375
Giannini, Courtney M; Herrick, Robert L; Buckholz, Jeanette M et al. (2018) Comprehension and perceptions of study participants upon receiving perfluoroalkyl substance exposure biomarker results. Int J Hyg Environ Health 221:1040-1046
Haque, Sulsal-Ul; Niu, Liang; Kuhnell, Damaris et al. (2018) Differential expression and prognostic value of long non-coding RNA in HPV-negative head and neck squamous cell carcinoma. Head Neck 40:1555-1564

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