Abstract

The overall goal of this Core is to investigate the genetic determinants and molecular mechanisms controlling pulmonary diseases induced or exacerbated by environmental agents. Research areas include the genetic basis of increased susceptibility to ozone or oxidant injury, the effects of ozone on surfactants proteins A and B, receptor G-protein coupling and other genetic determinants of asthma, gene transcription regulated by changes in oxygen concentration, and use of transgenic mouse models to study the molecular biology of pulmonary disease.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Environmental Health Sciences (NIEHS)
Type
Center Core Grants (P30)
Project #
3P30ES006096-08S1
Application #
6366988
Study Section
Project Start
1999-04-01
Project End
2000-03-31
Budget Start
1998-10-01
Budget End
1999-09-30
Support Year
8
Fiscal Year
2000
Total Cost
$156,647
Indirect Cost

  Institution

Name
University of Cincinnati
Department
Type
DUNS #
City
Cincinnati
State
OH
Country
United States
Zip Code
45221

  Publications

Bhattacharya, Sukanta S; Yadav, Jagjit S (2018) Microbial P450 Enzymes in Bioremediation and Drug Discovery: Emerging Potentials and Challenges. Curr Protein Pept Sci 19:75-86
VonHandorf, Andrew; Sánchez-Martín, Francisco Javier; Biesiada, Jacek et al. (2018) Chromium disrupts chromatin organization and CTCF access to its cognate sites in promoters of differentially expressed genes. Epigenetics 13:363-375
Giannini, Courtney M; Herrick, Robert L; Buckholz, Jeanette M et al. (2018) Comprehension and perceptions of study participants upon receiving perfluoroalkyl substance exposure biomarker results. Int J Hyg Environ Health 221:1040-1046
Haque, Sulsal-Ul; Niu, Liang; Kuhnell, Damaris et al. (2018) Differential expression and prognostic value of long non-coding RNA in HPV-negative head and neck squamous cell carcinoma. Head Neck 40:1555-1564
Zhang, Hongmei; Yolton, Kimberly; Webster, Glenys M et al. (2018) Prenatal and childhood perfluoroalkyl substances exposures and children's reading skills at ages 5 and 8years. Environ Int 111:224-231
Sharma, Manju; Zhang, Xiang; Huang, Shouxiong (2018) Integrate Imaging Flow Cytometry and Transcriptomic Profiling to Evaluate Altered Endocytic CD1d Trafficking. J Vis Exp :
Vuong, Ann M; Braun, Joseph M; Webster, Glenys M et al. (2018) Polybrominated diphenyl ether (PBDE) exposures and thyroid hormones in children at age 3?years. Environ Int 117:339-347
Pugh, Amanda M; Giannini, Courtney M; Pinney, Susan M et al. (2018) Characteristics and diagnosis of pregnancy and lactation associated breast cancer: Analysis of a self-reported regional registry. Am J Surg 216:809-812
Brunst, Kelly J; Tignor, Nicole; Just, Allan et al. (2018) Cumulative lifetime maternal stress and epigenome-wide placental DNA methylation in the PRISM cohort. Epigenetics 13:665-681
Alexander, Jacqueline; Teague, April M; Chen, Jing et al. (2018) Offspring sex impacts DNA methylation and gene expression in placentae from women with diabetes during pregnancy. PLoS One 13:e0190698

Showing the most recent 10 out of 979 publications