Abstract

The Southwest Environmental Health Sciences Center (SWEHSC) Pilot Projects program facilitates the implementation of the SWEHSC strategic vision and goal of testing the most innovative ideas relevant to environmental health by fostering opportunities to fill important gaps in the SWEHSC research portfolio. To date, the Pilot Project Program has enabled the successful creation of several scientifically productive collaborations that have emphasized the strengths of the SWEHSC in the conduct of translational studies and aided in securing significant extramural research funds for SWEHSC investigators. To support the SWEHSC strategic vision, the Pilot Projects program provides short-term support for innovative projects that explore new areas of environmental health research or that aim to acquire the preliminary data necessary to pursue long-term extramural funding. As well, the Pilot Projects program supports the Career Development of new investigators and highly successful senior investigators wishing to redirect their research to encompass environmental health.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Environmental Health Sciences (NIEHS)
Type
Center Core Grants (P30)
Project #
5P30ES006694-23
Application #
9942450
Study Section
Environmental Health Sciences Review Committee (EHS)
Project Start
Project End
Budget Start
2020-04-01
Budget End
2021-03-31
Support Year
23
Fiscal Year
2020
Total Cost
Indirect Cost

  Institution

Name
University of Arizona
Department
Type
DUNS #
806345617
City
Tucson
State
AZ
Country
United States
Zip Code
85721

  Publications

Dodson, Matthew; Liu, Pengfei; Jiang, Tao et al. (2018) Increased O-GlcNAcylation of SNAP29 drives arsenic-induced autophagic dysfunction. Mol Cell Biol :
Griggs, Chanel A; Malm, Scott W; Jaime-Frias, Rosa et al. (2018) Valproic acid disrupts the oscillatory expression of core circadian rhythm transcription factors. Toxicol Appl Pharmacol 339:110-120
Toth, Erica L; Li, Hui; Dzierlenga, Anika L et al. (2018) Gene-by-Environment Interaction of Bcrp-/- and Methionine- and Choline-Deficient Diet-Induced Nonalcoholic Steatohepatitis Alters SN-38 Disposition. Drug Metab Dispos 46:1478-1486
Malm, S W; Amouzougan, E A; Klimecki, W T (2018) Fetal bovine serum induces sustained, but reversible, epithelial-mesenchymal transition in the BEAS-2B cell line. Toxicol In Vitro 50:383-390
Rojo de la Vega, Montserrat; Zhang, Donna D; Wondrak, Georg T (2018) Topical Bixin Confers NRF2-Dependent Protection Against Photodamage and Hair Graying in Mouse Skin. Front Pharmacol 9:287
Harris, Alondra P; Ismail, Kareem A; Nunez, Martha et al. (2018) Trichloroethylene perturbs HNF4a expression and activity in the developing chick heart. Toxicol Lett 285:113-120
Dzierlenga, Anika L; Cherrington, Nathan J (2018) Misregulation of membrane trafficking processes in human nonalcoholic steatohepatitis. J Biochem Mol Toxicol 32:e22035
Yellowhair, Monica; Romanotto, Michelle R; Stearns, Diane M et al. (2018) Uranyl acetate induced DNA single strand breaks and AP sites in Chinese hamster ovary cells. Toxicol Appl Pharmacol 349:29-38
Wales, Jessica A; Chen, Cheng-Yu; Breci, Linda et al. (2018) Discovery of stimulator binding to a conserved pocket in the heme domain of soluble guanylyl cyclase. J Biol Chem 293:1850-1864
Munoz, Frances M; Zhang, Fengjiao; Islas-Robles, Argel et al. (2017) From the Cover: ROS-Induced Store-Operated Ca2+ Entry Coupled to PARP-1 Hyperactivation Is Independent of PARG Activity in Necrotic Cell Death. Toxicol Sci 158:444-453

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