Abstract

The core has three overall goals: 1) to facilitate the development of research projects to identify and study the ethical, social, and policy questions that are raised by clinical or public health use of ecogenetic research findings, especially in relation to high frequency, low penetrance genetic polymorphisms; 2) to develop and implement education strategies and materials that address the ethical, legal, social, and policy implications of ecogenetic research for several target audiences, including graduate students, CEEH investigators and trainees, health professionals, and community groups; and 3) to provide a service to other Center investigators by maintaining the existing CEEH """"""""Registry for the Study of Genetic and Environmental Risk Factors"""""""" and by providing consultation to Center Investigators by Environmental Risk Factors"""""""" and by providing consultation to Center investigators on ethical, legal, and policy issues, including informed consent, for genetic studies involving human subjects.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Environmental Health Sciences (NIEHS)
Type
Center Core Grants (P30)
Project #
2P30ES007033-06
Application #
6331696
Study Section
Environmental Health Sciences Review Committee (EHS)
Project Start
1995-04-01
Project End
2005-03-31
Budget Start
Budget End
Support Year
6
Fiscal Year
2000
Total Cost
$117,868
Indirect Cost

  Institution

Name
University of Washington
Department
Type
DUNS #
135646524
City
Seattle
State
WA
Country
United States
Zip Code
98195

  Publications

Kim, Young Hun; Jo, Mi Seong; Kim, Jin Kwon et al. (2018) Short-term inhalation study of graphene oxide nanoplates. Nanotoxicology 12:224-238
Woods, Nancy Fugate; Cray, Lori A; Mitchell, Ellen Sullivan et al. (2018) Polymorphisms in Estrogen Synthesis Genes and Symptom Clusters During the Menopausal Transition and Early Postmenopause: Observations From the Seattle Midlife Women's Health Study. Biol Res Nurs 20:153-160
Lee, Ji Hyun; Gulumian, Mary; Faustman, Elaine M et al. (2018) Blood Biochemical and Hematological Study after Subacute Intravenous Injection of Gold and Silver Nanoparticles and Coadministered Gold and Silver Nanoparticles of Similar Sizes. Biomed Res Int 2018:8460910
Weldon, Brittany A; Griffith, William C; Workman, Tomomi et al. (2018) In vitro to in vivo benchmark dose comparisons to inform risk assessment of quantum dot nanomaterials. Wiley Interdiscip Rev Nanomed Nanobiotechnol 10:e1507
Dempsey, Joseph; Zhang, Angela; Cui, Julia Yue (2018) Coordinate regulation of long non-coding RNAs and protein-coding genes in germ-free mice. BMC Genomics 19:834
Rooney, James P K; Woods, Nancy F; Martin, Michael D et al. (2018) Genetic polymorphisms of GRIN2A and GRIN2B modify the neurobehavioral effects of low-level lead exposure in children. Environ Res 165:1-10
Chang, Yu-Chi; Cole, Toby B; Costa, Lucio G (2018) Prenatal and early-life diesel exhaust exposure causes autism-like behavioral changes in mice. Part Fibre Toxicol 15:18
Li, Cindy Yanfei; Dempsey, Joseph L; Wang, Dongfang et al. (2018) PBDEs Altered Gut Microbiome and Bile Acid Homeostasis in Male C57BL/6 Mice. Drug Metab Dispos 46:1226-1240
Khan, Burhan A; Robinson, Renee; Fohner, Alison E et al. (2018) Cytochrome P450 Genetic Variation Associated with Tamoxifen Biotransformation in American Indian and Alaska Native People. Clin Transl Sci 11:312-321
Tanner, Julie-Anne; Zhu, Andy Z; Claw, Katrina G et al. (2018) Novel CYP2A6 diplotypes identified through next-generation sequencing are associated with in-vitro and in-vivo nicotine metabolism. Pharmacogenet Genomics 28:7-16

Showing the most recent 10 out of 711 publications