The Pilot Projects Program is intended to support six exploratory research projects related to the theme, """"""""Mechanisms Underlying Human Variability in Response to Environmental Exposures."""""""" The goals of the program are to: (1) stimulate CEEH investigators to initiate novel studies in the area of ecogenetics; (2) attract University of Washington scientists not currently working in ecogenetics and related fields to this area; (3) develop preliminary data to serve as a basis for future NIH research grants; and (4) encourage collaborative and inter-disciplinary work. Proposals will be solicited from CEEH and non- CEEH university investigators annually. Evaluation criteria will be weighted by scientific merit (50%), relevance to aims and goals of the CEEH (25%), collaborative and interdisciplinary involvement (12.5%), and use of CEEH facilities (12.5%). Proposals will be peer-reviewed by one referee from the University of Washington and one external evaluator, with final funding recommendations by the CEEH Executive external evaluator, with final funding recommendations by the CEEH Executive Committee. The Pilot Projects Program was expanded during the last year to include pilot grants in Ethical, Legal, and Social Issues of ecogenetics (ELSI). The latter category of proposals will be evaluated by appropriate experts, with final decision making to include input from 1-2 faculty members from the University of Washington Public Health Genetics Program (PHG).

Agency
National Institute of Health (NIH)
Institute
National Institute of Environmental Health Sciences (NIEHS)
Type
Center Core Grants (P30)
Project #
2P30ES007033-06
Application #
6331700
Study Section
Environmental Health Sciences Review Committee (EHS)
Project Start
1995-04-01
Project End
2005-03-31
Budget Start
Budget End
Support Year
6
Fiscal Year
2000
Total Cost
$117,873
Indirect Cost
Name
University of Washington
Department
Type
DUNS #
135646524
City
Seattle
State
WA
Country
United States
Zip Code
98195
Kim, Young Hun; Jo, Mi Seong; Kim, Jin Kwon et al. (2018) Short-term inhalation study of graphene oxide nanoplates. Nanotoxicology 12:224-238
Woods, Nancy Fugate; Cray, Lori A; Mitchell, Ellen Sullivan et al. (2018) Polymorphisms in Estrogen Synthesis Genes and Symptom Clusters During the Menopausal Transition and Early Postmenopause: Observations From the Seattle Midlife Women's Health Study. Biol Res Nurs 20:153-160
Lee, Ji Hyun; Gulumian, Mary; Faustman, Elaine M et al. (2018) Blood Biochemical and Hematological Study after Subacute Intravenous Injection of Gold and Silver Nanoparticles and Coadministered Gold and Silver Nanoparticles of Similar Sizes. Biomed Res Int 2018:8460910
Weldon, Brittany A; Griffith, William C; Workman, Tomomi et al. (2018) In vitro to in vivo benchmark dose comparisons to inform risk assessment of quantum dot nanomaterials. Wiley Interdiscip Rev Nanomed Nanobiotechnol 10:e1507
Dempsey, Joseph; Zhang, Angela; Cui, Julia Yue (2018) Coordinate regulation of long non-coding RNAs and protein-coding genes in germ-free mice. BMC Genomics 19:834
Rooney, James P K; Woods, Nancy F; Martin, Michael D et al. (2018) Genetic polymorphisms of GRIN2A and GRIN2B modify the neurobehavioral effects of low-level lead exposure in children. Environ Res 165:1-10
Chang, Yu-Chi; Cole, Toby B; Costa, Lucio G (2018) Prenatal and early-life diesel exhaust exposure causes autism-like behavioral changes in mice. Part Fibre Toxicol 15:18
Li, Cindy Yanfei; Dempsey, Joseph L; Wang, Dongfang et al. (2018) PBDEs Altered Gut Microbiome and Bile Acid Homeostasis in Male C57BL/6 Mice. Drug Metab Dispos 46:1226-1240
Khan, Burhan A; Robinson, Renee; Fohner, Alison E et al. (2018) Cytochrome P450 Genetic Variation Associated with Tamoxifen Biotransformation in American Indian and Alaska Native People. Clin Transl Sci 11:312-321
Tanner, Julie-Anne; Zhu, Andy Z; Claw, Katrina G et al. (2018) Novel CYP2A6 diplotypes identified through next-generation sequencing are associated with in-vitro and in-vivo nicotine metabolism. Pharmacogenet Genomics 28:7-16

Showing the most recent 10 out of 711 publications