The main goals of this Core are to develop methods for analyzing relationships between exposure and host factors in the disease response and to assist other Center members both within the Research Core and another Cores in the application of the statistical methodologies. Finally the Core includes as one of its objectives training of graduate students in modern statistical methods. Core members have long-standing, substantial support for their work primarily from NIH. Four large research projects are currently the focus of this Core. These include: time related factors in cancer epidemiology, methodologic research in genetic epidemiology, statistical methods and air pollution epidemiology and methods for dealing with exposure measurement error. In all cases, significant issues in study design, statistics and epidemiology are being addressed by the development of new approaches. All the issues being addressed in this work are related to human health consequences of exposure to environmental toxicants. The group meets weekly for reviews of recent activities and an informal seminar. Graduate students are included so they can discuss their work and receive feedback from the faculty. The external interactions are primarily with the Respiratory Effects Research Core. It appears that additional work is underway to tie together the respiratory Effects Exposure Assessment Research Core with the Molecular Biology and Sample Processing, and Biostatistics Facility Cores.

Agency
National Institute of Health (NIH)
Institute
National Institute of Environmental Health Sciences (NIEHS)
Type
Center Core Grants (P30)
Project #
5P30ES007048-07
Application #
6587868
Study Section
Project Start
2002-04-01
Project End
2003-03-31
Budget Start
Budget End
Support Year
7
Fiscal Year
2002
Total Cost
$117,873
Indirect Cost
Name
University of Southern California
Department
Type
DUNS #
041544081
City
Los Angeles
State
CA
Country
United States
Zip Code
90089
Kothari, Parul H; Qiu, Weiliang; Croteau-Chonka, Damien C et al. (2018) Role of local CpG DNA methylation in mediating the 17q21 asthma susceptibility gasdermin B (GSDMB)/ORMDL sphingolipid biosynthesis regulator 3 (ORMDL3) expression quantitative trait locus. J Allergy Clin Immunol 141:2282-2286.e6
Kerin, Tara; Volk, Heather; Li, Weiyan et al. (2018) Association Between Air Pollution Exposure, Cognitive and Adaptive Function, and ASD Severity Among Children with Autism Spectrum Disorder. J Autism Dev Disord 48:137-150
Goodrich, Amanda J; Volk, Heather E; Tancredi, Daniel J et al. (2018) Joint effects of prenatal air pollutant exposure and maternal folic acid supplementation on risk of autism spectrum disorder. Autism Res 11:69-80
Alderete, Tanya L; Jones, Roshonda B; Chen, Zhanghua et al. (2018) Exposure to traffic-related air pollution and the composition of the gut microbiota in overweight and obese adolescents. Environ Res 161:472-478
Felix, Janine F; Joubert, Bonnie R; Baccarelli, Andrea A et al. (2018) Cohort Profile: Pregnancy And Childhood Epigenetics (PACE) Consortium. Int J Epidemiol 47:22-23u
Chen, Honglei; Ritz, Beate (2018) The Search for Environmental Causes of Parkinson's Disease: Moving Forward. J Parkinsons Dis 8:S9-S17
Lee, Eunjung; Luo, Jianning; Schumacher, Fredrick R et al. (2018) Growth factor genes and change in mammographic density after stopping combined hormone therapy in the California Teachers Study. BMC Cancer 18:1072
Liu, Jie; Liang, Gangning; Siegmund, Kimberly D et al. (2018) Data integration by multi-tuning parameter elastic net regression. BMC Bioinformatics 19:369
Ejigu, Bedilu Alamirie; Wencheko, Eshetu; Berhane, Kiros (2018) Spatial pattern and determinants of anaemia in Ethiopia. PLoS One 13:e0197171
Herting, Megan M; Johnson, Cory; Mills, Kathryn L et al. (2018) Development of subcortical volumes across adolescence in males and females: A multisample study of longitudinal changes. Neuroimage 172:194-205

Showing the most recent 10 out of 653 publications