Abstract

The central goal of the Integrative Health Sciences Facility Core (IHSFC) is to provide Center investigators with services and resources that will facilitate the translation of basic research findings into clinical or public health applications. The general goals of the Core are to: ? Provide services, instrumentation and technologies that support the bench-to-bedside translation of basic science findings into clinical and public health applications. ? Support research to improve early detection, prevention, and/or therapy for disorders related to environmental exposures. ? Foster partnerships between researchers and community-based organizations and health agencies that will enhance the development and conduct of clinical and public health research. ? Educate Center investigators on the nature and requirements of clinical and public health research, including ethical, legal and social implications , and provide technical support for meeting human subjects, HIPAA and other human subjects research requirements. ? Facilitate clinical or public health-oriented pilot projects. ? Promote synergistic interactions with the Bioinformatics, Biostatistics and Computational Biology (BBCB) Facility Core.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Environmental Health Sciences (NIEHS)
Type
Center Core Grants (P30)
Project #
5P30ES014443-04
Application #
8055944
Study Section
Environmental Health Sciences Review Committee (EHS)
Project Start
Project End
Budget Start
2010-04-01
Budget End
2011-03-31
Support Year
4
Fiscal Year
2010
Total Cost
$274,249
Indirect Cost

  Institution

Name
University of Louisville
Department
Type
DUNS #
057588857
City
Louisville
State
KY
Country
United States
Zip Code
40292

  Publications

Montoya-Durango, Diego E; Ramos, Kenneth A; Bojang, Pasano et al. (2016) LINE-1 silencing by retinoblastoma proteins is effected through the nucleosomal and remodeling deacetylase multiprotein complex. BMC Cancer 16:38
Neal, Rachel E; Jagadapillai, Rekha; Chen, Jing et al. (2016) Developmental cigarette smoke exposure II: Kidney proteome profile alterations in 6 month old adult offspring. Reprod Toxicol 65:425-435
Bojang, Pasano; Ramos, Kenneth S (2016) Analysis of LINE-1 Retrotransposition at the Single Nucleus Level. J Vis Exp :
Llorens, M Candelaria; Lorenzatti, Guadalupe; Cavallo, Natalia L et al. (2016) Phosphorylation Regulates Functions of ZEB1 Transcription Factor. J Cell Physiol 231:2205-17
Neal, Rachel E; Chen, Jing; Webb, Cindy et al. (2016) Developmental cigarette smoke exposure II: Hepatic proteome profiles in 6 month old adult offspring. Reprod Toxicol 65:414-424
Xu, Xin; Prough, Russell A; Samuelson, David J (2015) Differential 12-O-Tetradecanoylphorbol-13-acetate-induced activation of rat mammary carcinoma susceptibility Fbxo10 variant promoters via a PKC-AP1 pathway. Mol Carcinog 54:134-47
Al-Eryani, Laila; Wahlang, Banrida; Falkner, K C et al. (2015) Identification of Environmental Chemicals Associated with the Development of Toxicant-associated Fatty Liver Disease in Rodents. Toxicol Pathol 43:482-97
Gordon, Michael W; Yan, Fang; Zhong, Xiaoming et al. (2015) Regulation of p53-targeting microRNAs by polycyclic aromatic hydrocarbons: Implications in the etiology of multiple myeloma. Mol Carcinog 54:1060-9
Bamji, Sanaya F; Page, Robert B; Patel, Dharti et al. (2015) Soy glyceollins regulate transcript abundance in the female mouse brain. Funct Integr Genomics 15:549-61
Ramos, Irma N; Appana, Savitri N; Brock, Guy et al. (2015) Health status, perceptions and needs of Hispanics in rural Shelbyville, Kentucky. J Immigr Minor Health 17:148-55

Showing the most recent 10 out of 183 publications