PILOT PROJECT PROGRAM ABSTRACT The overarching mission of the Pilot Project Program of the Center for Human Health and the Environment (CHHE) is to provide pilot funding to Center members and other NC State, East Carolina University (ECU), and NC Department of Health and Human Services (NC DHHS) investigators to collect preliminary data that will support applications for external funding from the National Institute of Environmental Health Sciences (NIEHS) . Important goals of the PPP are to foster the success of early stage investigators in EHS and to increase individual, collaborative, and multidisciplinary efforts to enhance and integrate research from molecular and cellular-based systems and model organisms to human population levels to address the fundamental mechanisms through which environmental exposures interface with the genome and epigenome to influence human disease. and other agencies supporting environmental health sciences (EHS) research The PPP is key to the success of the CHHE by: fostering early stage investigators, serving as a mechanism to recruit new scientists to EHS research; supporting innovative research initiatives that are difficult to fund at early stages; and cultivating cross-disciplinary projects that integrate basic, applied, clinical, and public health strengths of our Center. The PPP will support short-term projects to explore feasibility of new areas of study with a major emphasis on the effects and potential consequences of environmental exposures on human health. Funded pilot projects should lead to the collection of sufficient data to pursue support through extramural funding mechanisms. Consequently, the PPP will be the nexus for promoting an expansion of EHS research at NC State and ECU.

Public Health Relevance

The mission of the Pilot Project Program for the Center for Human Health and the Environment (CHHE) is to provide pilot funding to Center members and other NC State, East Carolina University (ECU), and NC Department of Health and Human Services (NC DHHS) investigators, in particular early stage investigators, to collect preliminary data that will support applications for external funding from the National Institute of Environmental Health Sciences (NIEHS) and other agencies supporting environmental health sciences research.

Agency
National Institute of Health (NIH)
Institute
National Institute of Environmental Health Sciences (NIEHS)
Type
Center Core Grants (P30)
Project #
1P30ES025128-01
Application #
8841242
Study Section
Environmental Health Sciences Review Committee (EHS)
Project Start
Project End
Budget Start
2015-04-20
Budget End
2016-03-31
Support Year
1
Fiscal Year
2015
Total Cost
$164,084
Indirect Cost
$55,778
Name
North Carolina State University Raleigh
Department
Type
DUNS #
042092122
City
Raleigh
State
NC
Country
United States
Zip Code
27695
Proaño, Stephanie B; Morris, Hannah J; Kunz, Lindsey M et al. (2018) Estrous cycle-induced sex differences in medium spiny neuron excitatory synaptic transmission and intrinsic excitability in adult rat nucleus accumbens core. J Neurophysiol 120:1356-1373
Messenger, Zachary J; Hall, Jonathan R; Jima, Dereje D et al. (2018) C/EBP? deletion in oncogenic Ras skin tumors is a synthetic lethal event. Cell Death Dis 9:1054
Kaur, Parminder; Longley, Matthew J; Pan, Hai et al. (2018) Single-molecule DREEM imaging reveals DNA wrapping around human mitochondrial single-stranded DNA binding protein. Nucleic Acids Res 46:11287-11302
Willett, Jaime A; Johnson, Ashlyn G; Vogel, Andrea R et al. (2018) Nucleus accumbens core medium spiny neuron electrophysiological properties and partner preference behavior in the adult male prairie vole, Microtus ochrogaster. J Neurophysiol 119:1576-1588
Bagley, M Caleb; Ekelöf, Måns; Rock, Kylie et al. (2018) IR-MALDESI mass spectrometry imaging of underivatized neurotransmitters in brain tissue of rats exposed to tetrabromobisphenol A. Anal Bioanal Chem 410:7979-7986
Marvel, Skylar W; To, Kimberly; Grimm, Fabian A et al. (2018) ToxPi Graphical User Interface 2.0: Dynamic exploration, visualization, and sharing of integrated data models. BMC Bioinformatics 19:80
Miyazawa, Masaki; Bogdan, Alexander R; Hashimoto, Kazunori et al. (2018) Regulation of transferrin receptor-1 mRNA by the interplay between IRE-binding proteins and miR-7/miR-141 in the 3'-IRE stem-loops. RNA 24:468-479
Venkatratnam, Abhishek; House, John S; Konganti, Kranti et al. (2018) Population-based dose-response analysis of liver transcriptional response to trichloroethylene in mouse. Mamm Genome 29:168-181
Green, Adrian J; Planchart, Antonio (2018) The neurological toxicity of heavy metals: A fish perspective. Comp Biochem Physiol C Toxicol Pharmacol 208:12-19
Benjamin Neelon, S E; White, A J; Vidal, A C et al. (2018) Maternal vitamin D, DNA methylation at imprint regulatory regions and offspring weight at birth, 1 year and 3 years. Int J Obes (Lond) 42:587-593

Showing the most recent 10 out of 118 publications