Abstract

The objectives of the Core Grant for Vision Research are: (1) to increase knowledge concerning normal vision; (2) to apply this knowledge to the preservation and restoration of human vision; To achieve these overall scientific goals, a multidisciplinary research program has been developed. Related to the eye and vision, this program consists of the following major basic science and clinical research components: Molecular Biology, Biochemistry, Electrophysiology, Microbiology and Immunology, Ophthalmic Pathology, Ophthalmology--Retina and Lens Disease Research, Ophthalmology--Sensory and Motor Disease Research, and Pediatric Ophthalmology Research. Appropriately interrelated, the major components of this program apply a wide spectrum of laboratory and clinical methods of investigation to an extensive array of research projects. The support requested is for the following core modules: biochemistry, photography, pathology, computer, and electron microscopy.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Eye Institute (NEI)
Type
Center Core Grants (P30)
Project #
5P30EY000331-22
Application #
3102392
Study Section
Vision Research and Training Committee (VSN)
Project Start
1978-11-01
Project End
1989-02-28
Budget Start
1987-12-01
Budget End
1989-02-28
Support Year
22
Fiscal Year
1988
Total Cost
Indirect Cost

  Institution

Name
University of California Los Angeles
Department
Type
Schools of Medicine
DUNS #
119132785
City
Los Angeles
State
CA
Country
United States
Zip Code
90095

  Publications

Zhang, Xiang-Mei; Hashimoto, Takao; Tang, Ronald et al. (2018) Elevated expression of human bHLH factor ATOH7 accelerates cell cycle progression of progenitors and enhances production of avian retinal ganglion cells. Sci Rep 8:6823
Chaudhuri, Zia; Demer, Joseph L (2018) Long-term Surgical Outcomes in the Sagging Eye Syndrome. Strabismus 26:6-10
Esteve-Rudd, Julian; Hazim, Roni A; Diemer, Tanja et al. (2018) Defective phagosome motility and degradation in cell nonautonomous RPE pathogenesis of a dominant macular degeneration. Proc Natl Acad Sci U S A 115:5468-5473
Morshedian, Ala; Woodruff, Michael L; Fain, Gordon L (2018) Role of recoverin in rod photoreceptor light adaptation. J Physiol 596:1513-1526
Glasgow, Ben J; Abduragimov, Adil R (2018) Interaction of ceramides and tear lipocalin. Biochim Biophys Acta Mol Cell Biol Lipids 1863:399-408
Demer, Joseph L (2018) Knobby Eye Syndrome. Strabismus 26:33-41
Glasgow, Ben J; Abduragimov, Adil R (2018) Ligand binding studies by high speed centrifugal precipitation and linear spectral summation using ultraviolet-visible absorption spectroscopy. MethodsX 5:345-351
Hazim, Roni A; Volland, Stefanie; Yen, Alice et al. (2018) Rapid differentiation of the human RPE cell line, ARPE-19, induced by nicotinamide. Exp Eye Res 179:18-24
Glasgow, Ben J; Abduragimov, Adil R (2018) Data on Orphan tear lipid analogs, synthesis and binding to tear lipocalin. Data Brief 18:999-1004
Sarria, Ignacio; Cao, Yan; Wang, Yuchen et al. (2018) LRIT1 Modulates Adaptive Changes in Synaptic Communication of Cone Photoreceptors. Cell Rep 22:3562-3573

Showing the most recent 10 out of 289 publications