The Noninvasive Assessment of Visual Function Core Module (NACM) has provides resources for the assessment of visual function in laboratory animals. These services are particularly useful in assessing the effects of retinal disease and of therapies that target such disease. The module designs custom testing protocols that are effective for specific research projects, maintains and consolidates equipment for its most effective use by VRC investigators, promotes collaboration and technique sharing across VRC labs, designs and builds (in cooperation with the Instrumentation Core Module) new experimental setups if no adequate commercial equipment is available, trains lab personnel, develops custom software for advanced data processing (in collaboration with the Image Analysis Core Module), consults on data processing, paper and grant preparation, and responses to reviewers.
| Guziewicz, Karina E; Cideciyan, Artur V; Beltran, William A et al. (2018) BEST1 gene therapy corrects a diffuse retina-wide microdetachment modulated by light exposure. Proc Natl Acad Sci U S A 115:E2839-E2848 |
| Chen, Xi; Mangalesh, Shwetha; Dandridge, Alexandria et al. (2018) Spectral-Domain OCT Findings of Retinal Vascular-Avascular Junction in Infants with Retinopathy of Prematurity. Ophthalmol Retina 2:963-971 |
| Dhingra, Anuradha; Bell, Brent A; Peachey, Neal S et al. (2018) Microtubule-Associated Protein 1 Light Chain 3B, (LC3B) Is Necessary to Maintain Lipid-Mediated Homeostasis in the Retinal Pigment Epithelium. Front Cell Neurosci 12:351 |
| Mattar, Marcelo G; Olkkonen, Maria; Epstein, Russell A et al. (2018) Adaptation decorrelates shape representations. Nat Commun 9:3812 |
| Cideciyan, Artur V; Sudharsan, Raghavi; Dufour, Valérie L et al. (2018) Mutation-independent rhodopsin gene therapy by knockdown and replacement with a single AAV vector. Proc Natl Acad Sci U S A 115:E8547-E8556 |
| Zhang, Harrison G; Ying, Gui-Shuang (2018) Statistical approaches in published ophthalmic clinical science papers: a comparison to statistical practice two decades ago. Br J Ophthalmol 102:1188-1191 |
| Huang, Jing; Huang, Jiayan; Chen, Yong et al. (2018) Evaluation of Approaches to Analyzing Continuous Correlated Eye Data When Sample Size Is Small. Ophthalmic Epidemiol 25:45-54 |
| Gómez, Néstor Más; Lu, Wennan; Lim, Jason C et al. (2018) Robust lysosomal calcium signaling through channel TRPML1 is impaired by lysosomal lipid accumulation. FASEB J 32:782-794 |
| Morgan, Jessica I W; Vergilio, Grace K; Hsu, Jessica et al. (2018) The Reliability of Cone Density Measurements in the Presence of Rods. Transl Vis Sci Technol 7:21 |
| Chakraborty, Ranjay; Ostrin, Lisa A; Nickla, Debora L et al. (2018) Circadian rhythms, refractive development, and myopia. Ophthalmic Physiol Opt 38:217-245 |
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