The long-term objectives of this project are to conduct clinial studies which will provide new information for understanding, prevention, and management of disorders of the visual system. The first specific aim is to establish a Clinical Reserach CORE Module that will include a biostatistician, clinical coordinator, and computer. This new module will enhance existing and new clinical research projects by providing epidemiologic and biostatistical methodology necessary for conduct of prospective clinical trials, using state-of-the-art data analysis. Examples of projects include: Japanese- American community diabetes study, Yakima diabetic eye screening project, optic neuritis treatment trial, effect of somatostatin analogs on diabetic retinopathy, analysis of dissemination of new knowledge obtained from clinical trials, evaluation of automated perimetry software, evaluation of infant vision testing cards, treatment of Graves' ophthalmopathy, use of intraocular lenses in diabetic patients, clinical pathologic study of eyes from Alzheimer's patients, genetic analysis of ocular coloboma, and application of gene probes for retinal proteins to DNA from patients with inherited retinal dystrophies, including retinitis pigmentosa.
| Bleckert, Adam; Zhang, Chi; Turner, Maxwell H et al. (2018) GABA release selectively regulates synapse development at distinct inputs on direction-selective retinal ganglion cells. Proc Natl Acad Sci U S A 115:E12083-E12090 |
| Kerov, Vasily; Laird, Joseph G; Joiner, Mei-Ling et al. (2018) ?2?-4 Is Required for the Molecular and Structural Organization of Rod and Cone Photoreceptor Synapses. J Neurosci 38:6145-6160 |
| Pepple, Kathryn L; Wilson, Leslie; Van Gelder, Russell N (2018) Comparison of Aqueous and Vitreous Lymphocyte Populations From Two Rat Models of Experimental Uveitis. Invest Ophthalmol Vis Sci 59:2504-2511 |
| Lee, Cecilia S; Lee, Aaron Y; Akileswaran, Lakshmi et al. (2018) Determinants of Outcomes of Adenoviral Keratoconjunctivitis. Ophthalmology 125:1344-1353 |
| Coates, Daniel R; Levi, Dennis M; Touch, Phanith et al. (2018) Foveal Crowding Resolved. Sci Rep 8:9177 |
| Gordon, Sharona E; Munari, Mika; Zagotta, William N (2018) Visualizing conformational dynamics of proteins in solution and at the cell membrane. Elife 7: |
| Pedersen, Hilde R; Hagen, Lene A; Landsend, Erlend C S et al. (2018) Color Vision in Aniridia. Invest Ophthalmol Vis Sci 59:2142-2152 |
| Chao, Cecilia; Akileswaran, Lakshmi; Cooke Bailey, Jessica N et al. (2018) Potential Role of Ocular Microbiome, Host Genotype, Tear Cytokines, and Environmental Factors in Corneal Infiltrative Events in Contact Lens Wearers. Invest Ophthalmol Vis Sci 59:5752-5761 |
| Yu, Wan-Qing; El-Danaf, Rana N; Okawa, Haruhisa et al. (2018) Synaptic Convergence Patterns onto Retinal Ganglion Cells Are Preserved despite Topographic Variation in Pre- and Postsynaptic Territories. Cell Rep 25:2017-2026.e3 |
| Cabrera, Michelle T; Enyedi, Laura B; Ding, Leona et al. (2018) Sexual Harassment in Ophthalmology: A Survey Study. Ophthalmology : |
Showing the most recent 10 out of 556 publications
