Systems Biology Services and Shared Instrumentation Component: Project Summary The objective of the Vision Research Core is to enhance the productivity and efficiency of the research programs of the UW vision scientists, with special priority given to investigators holding NEI R01 grants. The core achieves this objective by: (1) giving investigators and their laboratory personnel access to resources that are outside the resources of individual R01 grants, (2) giving investigators and their laboratory personnel access to technical expertise that is outside the scope of individual labs, (3) providing training of laboratory personnel to enhance the capacity of individual labs, and (4) providing a culture that promotes collaboration. The Systems Biology Services and Shared Instrumentation Component achieves this goal ? by providing access to state-of-the-art instrumentation for in vivo and ex vivo functional analysis of the visual system ? by providing access to state-of-the-art instrumentation for in vivo imaging of retina, including detection of fluorescent proteins ? providing state-of-the-art light sources and calibration instruments for developing visual stimuli for functional experiments ? by providing technical assistance and training in use of the component?s shared instruments

Agency
National Institute of Health (NIH)
Institute
National Eye Institute (NEI)
Type
Center Core Grants (P30)
Project #
5P30EY001730-44
Application #
9767192
Study Section
Special Emphasis Panel (ZEY1)
Project Start
Project End
Budget Start
2019-09-01
Budget End
2020-08-31
Support Year
44
Fiscal Year
2019
Total Cost
Indirect Cost
Name
University of Washington
Department
Type
DUNS #
605799469
City
Seattle
State
WA
Country
United States
Zip Code
98195
Schmidt, Brian P; Sabesan, Ramkumar; Tuten, William S et al. (2018) Sensations from a single M-cone depend on the activity of surrounding S-cones. Sci Rep 8:8561
Wool, Lauren E; Crook, Joanna D; Troy, John B et al. (2018) Nonselective Wiring Accounts for Red-Green Opponency in Midget Ganglion Cells of the Primate Retina. J Neurosci 38:1520-1540
Leonard, Andrea; Bertero, Alessandro; Powers, Joseph D et al. (2018) Afterload promotes maturation of human induced pluripotent stem cell derived cardiomyocytes in engineered heart tissues. J Mol Cell Cardiol 118:147-158
Arbach, Hannah E; Harland-Dunaway, Marcus; Chang, Jessica K et al. (2018) Extreme nuclear branching in healthy epidermal cells of the Xenopus tail fin. J Cell Sci 131:
Pallus, Adam C; Walton, Mark M G; Mustari, Michael J (2018) Activity of near response cells during disconjugate saccades in strabismic monkeys. J Neurophysiol :
Kojima, Yoshiko; Soetedjo, Robijanto (2018) Elimination of the error signal in the superior colliculus impairs saccade motor learning. Proc Natl Acad Sci U S A 115:E8987-E8995
Manookin, Michael B; Patterson, Sara S; Linehan, Conor M (2018) Neural Mechanisms Mediating Motion Sensitivity in Parasol Ganglion Cells of the Primate Retina. Neuron 97:1327-1340.e4
Giarmarco, Michelle M; Cleghorn, Whitney M; Hurley, James B et al. (2018) Preparing Fresh Retinal Slices from Adult Zebrafish for Ex Vivo Imaging Experiments. J Vis Exp :
Patterson, Emily J; Kalitzeos, Angelos; Kasilian, Melissa et al. (2018) Residual Cone Structure in Patients With X-Linked Cone Opsin Mutations. Invest Ophthalmol Vis Sci 59:4238-4248
Pepple, Kathryn L; Nguyen, Macklin H; Pakzad-Vaezi, Kaivon et al. (2018) RESPONSE OF INFLAMMATORY CYSTOID MACULAR EDEMA TO TREATMENT USING ORAL ACETAZOLAMIDE. Retina :

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