- BIOSTATISTICS The Wilmer Biostatistics Center (WBC) has been successful in providing study design and analytic support to funded Wilmer faculty through its flexible structure that combines the expertise of Wilmer biostatisticians and epidemiologists with consultants at Department of Biostatistics at Johns Hopkins Bloomberg School of Public. The WBC has facilitated interdisciplinary collaboration across schools and across institutions through funding that supports outside consultants. It has also promoted productivity by providing statistical resources to faculty in a timely and cost-efficient manner. As Wilmer researchers become more successful and expand their research portfolios, the WBC is committed to innovating to provide more expansive sustainable services through innovative enhancements. The WBC web presence is expanding to provide more visibility and accessibility, and harnessing web-based assessment tools to refine capture of metrics of success ? information that will help the WBC grow and improve. The WBC is also expanding capacity into new and current data sources, which will allow researchers to harness current research trends in big data sources and sophisticated ophthalmic imaging modalities. The WBC is going beyond providing analytic services to train Wilmer researchers to be savvy consumers of statistical output. The goal of the WBC is to grow and adapt with Wilmer researchers to provide expert reliable analytic services and consulting as well as push frontiers of research in Wilmer through education initiatives, collaboration facilitation, methodological development and capacity building. In the current proposed funding period, the center will 1) continue to provide expert and specialized biostatistics and epidemiology services for ophthalmology research; 2) develop improved tracking of outcomes through web-based technology; 3) refine the WBC business plan to improve transparency and standardize service quality; 4) expand training and educational resources for investigators; and 5) build capacity in new areas of big data.

Agency
National Institute of Health (NIH)
Institute
National Eye Institute (NEI)
Type
Center Core Grants (P30)
Project #
2P30EY001765-44
Application #
9795548
Study Section
Special Emphasis Panel (ZEY1)
Project Start
Project End
Budget Start
2019-09-01
Budget End
2020-07-31
Support Year
44
Fiscal Year
2019
Total Cost
Indirect Cost
Name
Johns Hopkins University
Department
Type
DUNS #
001910777
City
Baltimore
State
MD
Country
United States
Zip Code
21205
Sharma, Anjali; Porterfield, Joshua E; Smith, Elizabeth et al. (2018) Effect of mannose targeting of hydroxyl PAMAM dendrimers on cellular and organ biodistribution in a neonatal brain injury model. J Control Release 283:175-189
Kimball, Elizabeth C; Jefferys, Joan L; Pease, Mary E et al. (2018) The effects of age on mitochondria, axonal transport, and axonal degeneration after chronic IOP elevation using a murine ocular explant model. Exp Eye Res 172:78-85
Nesper, Peter L; Lutty, Gerard A; Fawzi, Amani A (2018) RESIDUAL CHOROIDAL VESSELS IN ATROPHY CAN MASQUERADE AS CHOROIDAL NEOVASCULARIZATION ON OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY: Introducing a Clinical and Software Approach. Retina 38:1289-1300
Gilbert-Honick, Jordana; Ginn, Brian; Zhang, Yuanfan et al. (2018) Adipose-derived Stem/Stromal Cells on Electrospun Fibrin Microfiber Bundles Enable Moderate Muscle Reconstruction in a Volumetric Muscle Loss Model. Cell Transplant :963689718805370
Zhang, Zhi; Jyoti, Amar; Balakrishnan, Bindu et al. (2018) Trajectory of inflammatory and microglial activation markers in the postnatal rabbit brain following intrauterine endotoxin exposure. Neurobiol Dis 111:153-162
Bressler, Eric M; Kim, Jayoung; Shmueli, Ron B et al. (2018) Biomimetic peptide display from a polymeric nanoparticle surface for targeting and antitumor activity to human triple-negative breast cancer cells. J Biomed Mater Res A 106:1753-1764
Liu, Yuanyuan; Fortmann, Seth D; Shen, Jikui et al. (2018) AAV8-antiVEGFfab Ocular Gene Transfer for Neovascular Age-Related Macular Degeneration. Mol Ther 26:542-549
Bhutto, Imran A; Ogura, Shuntaro; Baldeosingh, Rajkumar et al. (2018) An Acute Injury Model for the Phenotypic Characteristics of Geographic Atrophy. Invest Ophthalmol Vis Sci 59:AMD143-AMD151
Wilson, David R; Sen, Rupashree; Sunshine, Joel C et al. (2018) Biodegradable STING agonist nanoparticles for enhanced cancer immunotherapy. Nanomedicine 14:237-246
Fernandes, Kimberly A; Mitchell, Katherine L; Patel, Amit et al. (2018) Role of SARM1 and DR6 in retinal ganglion cell axonal and somal degeneration following axonal injury. Exp Eye Res 171:54-61

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