Abstract

CELLULAR AND MOLECULAR BIOLOGY CORE The Cellular and Molecular Biology Core provides essential equipment and support for molecular biology, cell culture, histology, and virology. Importantly, the Core contains a number of specialized instruments that are either too costly for individual investigators, necessary but infrequently used, or require skilled assistance to use. The goals are to provide facilities, expertise, and services for: 1) establishing, expanding, and maintaining primary cells, stem cells, and transformed, transfected, and inducible cell lines as well as organ cultures for use in vision research, 2) performing cellular and molecular biology experiments for ophthalmic research that require use of specialized instrumentation, 3) assisting and coordinating experiments that involve cell culturing, transfection, viral packaging, primer design, cloning, construction of mammalian and viral vectors, flow cytometry, laser capture microdissection, DNA sequencing, real time PCR, DNA/microRNA microarray, Luminex, proteomics, and protein analyses, and 4) assisting in histologic and morphological studies of tissue specimens and cultured cells.

Public Health Relevance

CELLULAR AND MOLECULAR BIOLOGY CORE The Cellular and Molecular Biology Core provides facilities, equipment, and support for cellular and molecular biology to augment research capacity and increase productivity of investigators.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Eye Institute (NEI)
Type
Center Core Grants (P30)
Project #
5P30EY001792-39
Application #
9562094
Study Section
Special Emphasis Panel (ZEY1)
Project Start
Project End
Budget Start
2018-09-30
Budget End
2019-09-29
Support Year
39
Fiscal Year
2018
Total Cost
Indirect Cost

  Institution

Name
University of Illinois at Chicago
Department
Type
DUNS #
098987217
City
Chicago
State
IL
Country
United States
Zip Code
60612

  Publications

Roth, Steven; Dreixler, John; Newman, Nancy J (2018) Haemodilution and head-down tilting induce functional injury in the rat optic nerve: A model for peri-operative ischemic optic neuropathy. Eur J Anaesthesiol 35:840-847
Blair, Norman P; Tan, Michael R; Felder, Anthony E et al. (2018) Retinal tissue oxygen tension and consumption during light flicker stimulation in rat. Exp Eye Res 175:207-211
Son, Taeyoon; Alam, Minhaj; Toslak, Devrim et al. (2018) Functional optical coherence tomography of neurovascular coupling interactions in the retina. J Biophotonics 11:e201800089
Gao, X Raymond; Huang, Hua; Nannini, Drew R et al. (2018) Genome-wide association analyses identify new loci influencing intraocular pressure. Hum Mol Genet 27:2205-2213
Alam, Minhaj; Son, Taeyoon; Toslak, Devrim et al. (2018) Combining ODR and Blood Vessel Tracking for Artery-Vein Classification and Analysis in Color Fundus Images. Transl Vis Sci Technol 7:23
Francis, Andrew W; Wanek, Justin; Shahidi, Mahnaz (2018) Assessment of Global and Local Alterations in Retinal Layer Thickness in Ins2 (Akita) Diabetic Mice by Spectral Domain Optical Coherence Tomography. J Ophthalmol 2018:7253498
Toslak, Devrim; Ayata, Ali; Liu, Changgeng et al. (2018) WIDE-FIELD SMARTPHONE FUNDUS VIDEO CAMERA BASED ON MINIATURIZED INDIRECT OPHTHALMOSCOPY. Retina 38:438-441
Shahidi, Mahnaz; Felder, Anthony E; Tan, Ou et al. (2018) Retinal Oxygen Delivery and Metabolism in Healthy and Sickle Cell Retinopathy Subjects. Invest Ophthalmol Vis Sci 59:1905-1909
Cao, Dingcai; Chang, Adam; Gai, Shaoyan (2018) Evidence for an impact of melanopsin activation on unique white perception. J Opt Soc Am A Opt Image Sci Vis 35:B287-B291
Moss, Heather E; Vangipuram, Gautam; Shirazi, Zainab et al. (2018) Retinal Vessel Diameters Change Within 1 Hour of Intracranial Pressure Lowering. Transl Vis Sci Technol 7:6

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