Abstract

This is a center for research in various areas of the visual sciences that provides Core support to a nucleus of 12 independent investigators. The purpose of the center is to improve productivity and to enhance collaboration by providing common centralized services. The center is structured in 4 service units: Machine Shop; Photography and Illustration; Electronic-Instrumentation; and Administration. Research is conducted in several scientific disciplines such as: biochemistry, physiology, pharmacology, anatomy, neurology, and psychophysics including areas of vision research such as: glaucoma, electrophysiology and fluid transport in the cornea, lens, and ciliary body, aqueous humor dynamics, herpes simplex keratitis and bacterial infections of the cornea, biochemistry of cataracts, ERG and VEP in eye diseases, visual control of the oculomotor system, role of receptors in IOP regulation and morphology and function of central optic pathways.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Eye Institute (NEI)
Type
Center Core Grants (P30)
Project #
5P30EY001867-11
Application #
3102471
Study Section
Vision Research and Training Committee (VSN)
Project Start
1977-02-01
Project End
1990-06-30
Budget Start
1987-07-01
Budget End
1988-06-30
Support Year
11
Fiscal Year
1987
Total Cost
Indirect Cost

  Institution

Name
Mount Sinai School of Medicine
Department
Type
Schools of Medicine
DUNS #
City
New York
State
NY
Country
United States
Zip Code
10029

  Publications

Alvarez, Lawrence J; Zamudio, Aldo C; Candia, Oscar A (2013) Sildenafil stimulates aqueous humor turnover in rabbits. Exp Eye Res 111:67-70
Gerometta, Rosana; Kumar, Sandeep; Shah, Shaily et al. (2013) Reduction of steroid-induced intraocular pressure elevation in sheep by tissue plasminogen activator. Invest Ophthalmol Vis Sci 54:7903-9
Wang, Lingyan; Ly, Christine M; Ko, Chun-Ying et al. (2012) uPA binding to PAI-1 induces corneal myofibroblast differentiation on vitronectin. Invest Ophthalmol Vis Sci 53:4765-75
Gerometta, Rosana; Alvarez, Lawrence J; Candia, Oscar A (2012) Sildenafil accelerates anterior chamber refilling after paracentesis in sheep and rabbits. Invest Ophthalmol Vis Sci 53:565-73
Candia, Oscar A; Mathias, Richard; Gerometta, Rosana (2012) Fluid circulation determined in the isolated bovine lens. Invest Ophthalmol Vis Sci 53:7087-96
Wang, Lingyan; Pedroja, Benjamin S; Meyers, Erin E et al. (2012) Degradation of internalized ?v?5 integrin is controlled by uPAR bound uPA: effect on ?1 integrin activity and ?-SMA stress fiber assembly. PLoS One 7:e33915
Yakushin, Sergei B; Dai, Mingjia; Raphan, Theodore et al. (2011) Spatial orientation of the angular vestibulo-ocular reflex (aVOR) after semicircular canal plugging and canal nerve section. Exp Brain Res 210:583-94
Trexler, E Brady; Casti, Alexander R R; Zhang, Yu (2011) Nonlinearity and noise at the rod-rod bipolar cell synapse. Vis Neurosci 28:61-8
Xiao, Youping; Kavanau, Christopher; Bertin, Lauren et al. (2011) The biological basis of a universal constraint on color naming: cone contrasts and the two-way categorization of colors. PLoS One 6:e24994
Crumiller, Marshall; Knight, Bruce; Yu, Yunguo et al. (2011) Estimating the amount of information conveyed by a population of neurons. Front Neurosci 5:90

Showing the most recent 10 out of 338 publications