Abstract

The primary function of the Morphology Module is to make available to vision researchers both the instruments and expertise required to perform microscopic analyses of ocular specimens, subcellular fractions, or cultured cells. A centralized facility is essential since virtually all the lab scientists in our group must examine cell or tissue structure for some aspects of their work, but each individual cannot justify or support a fully-equipped microscopy lab (including an electron microscope), or the ongoing salaries of skilled microscopy technicians. The Module prepares specimens for light and electron microscopy, including special stains and histochemical reactions, and for immunofluorescence microscopy, confocal imaging and in situ hybridization.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Eye Institute (NEI)
Type
Center Core Grants (P30)
Project #
5P30EY001931-33
Application #
7802095
Study Section
Special Emphasis Panel (ZEY1)
Project Start
Project End
Budget Start
2009-04-01
Budget End
2010-03-31
Support Year
33
Fiscal Year
2009
Total Cost
$84,802
Indirect Cost

  Institution

Name
Medical College of Wisconsin
Department
Type
DUNS #
937639060
City
Milwaukee
State
WI
Country
United States
Zip Code
53226

  Publications

Reid, Christopher A; Nettesheim, Emily R; Connor, Thomas B et al. (2018) Development of an inducible anti-VEGF rAAV gene therapy strategy for the treatment of wet AMD. Sci Rep 8:11763
Zhang, Hanmeng; Mu, Lianwei; Wang, Dandan et al. (2018) Uncovering a critical period of synaptic imbalance during postnatal development of the rat visual cortex: role of brain-derived neurotrophic factor. J Physiol 596:4511-4536
Lewis, Tylor R; Kundinger, Sean R; Link, Brian A et al. (2018) Kif17 phosphorylation regulates photoreceptor outer segment turnover. BMC Cell Biol 19:25
Huckenpahler, Alison; Wilk, Melissa; Link, Brian et al. (2018) Repeatability and Reproducibility of In Vivo Cone Density Measurements in the Adult Zebrafish Retina. Adv Exp Med Biol 1074:151-156
Lewis, Tylor R; Zareba, Mariusz; Link, Brian A et al. (2018) Cone myoid elongation involves unidirectional microtubule movement mediated by dynein-1. Mol Biol Cell 29:180-190
Lee, Daniel J; Woertz, Erica N; Visotcky, Alexis et al. (2018) The Henle Fiber Layer in Albinism: Comparison to Normal and Relationship to Outer Nuclear Layer Thickness and Foveal Cone Density. Invest Ophthalmol Vis Sci 59:5336-5348
Linderman, Rachel E; Muthiah, Manickam N; Omoba, Sarah B et al. (2018) Variability of Foveal Avascular Zone Metrics Derived From Optical Coherence Tomography Angiography Images. Transl Vis Sci Technol 7:20
Vogel, Ryan N; Strampe, Margaret; Fagbemi, Oladipo E et al. (2018) Foveal Development in Infants Treated with Bevacizumab or Laser Photocoagulation for Retinopathy of Prematurity. Ophthalmology 125:444-452
Warren, Clinton C; Young, Jonathon B; Goldberg, Mara R et al. (2018) Findings in Persistent Retinopathy of Prematurity. Ophthalmic Surg Lasers Imaging Retina 49:497-503
Strampe, Margaret R; Huckenpahler, Alison L; Higgins, Brian P et al. (2018) Intraobserver Repeatability and Interobserver Reproducibility of Ellipsoid Zone Measurements in Retinitis Pigmentosa. Transl Vis Sci Technol 7:13

Showing the most recent 10 out of 517 publications