Abstract

Continuing support is requestd for Core Center facilities and services to strengthen and promote collaborative interactions between the sixteen vision researchers that comprise the Core faculty at the Cullen Eye Institute of Baylor College of Medicine. The major programmatic areas include diseases of the retina and choroid, the cornea and the sensory motor visual system. Research activities include investigation of the anatomy, biochemistry, physiology and pathology of the neural retina, retinal pigment epithelium and choroid, retinal organization and information processing, the role of herpes virus in corneal disease, endogenous fungal endophthalmitis and visual dysfunction of strabismus and amblyopia.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Eye Institute (NEI)
Type
Center Core Grants (P30)
Project #
5P30EY002520-10
Application #
3102526
Study Section
Vision Research and Training Committee (VSN)
Project Start
1979-07-01
Project End
1989-06-30
Budget Start
1988-07-01
Budget End
1989-06-30
Support Year
10
Fiscal Year
1988
Total Cost
Indirect Cost

  Institution

Name
Baylor College of Medicine
Department
Type
Schools of Medicine
DUNS #
074615394
City
Houston
State
TX
Country
United States
Zip Code
77030

  Publications

Dharmat, Rachayata; Eblimit, Aiden; Robichaux, Michael A et al. (2018) SPATA7 maintains a novel photoreceptor-specific zone in the distal connecting cilium. J Cell Biol 217:2851-2865
DuPont, Mariana; Jones, Evan M; Xu, Mingchu et al. (2018) Investigating the disease association of USH2A p.C759F variant by leveraging large retinitis pigmentosa cohort data. Ophthalmic Genet 39:291-292
Barrasso, Anthony P; Tong, Xuefei; Poché, Ross A (2018) The mito::mKate2 mouse: A far-red fluorescent reporter mouse line for tracking mitochondrial dynamics in vivo. Genesis 56:
Xiao, Yangyan; de Paiva, Cintia S; Yu, Zhiyuan et al. (2018) Goblet cell-produced retinoic acid suppresses CD86 expression and IL-12 production in bone marrow-derived cells. Int Immunol 30:457-470
Wang, Jun; Zhao, Li; Wang, Xia et al. (2018) GRIPT: a novel case-control analysis method for Mendelian disease gene discovery. Genome Biol 19:203
Wang, Hongxia; Dewell, Richard B; Zhu, Ying et al. (2018) Feedforward Inhibition Conveys Time-Varying Stimulus Information in a Collision Detection Circuit. Curr Biol 28:1509-1521.e3
Zhu, Ying; Dewell, Richard B; Wang, Hongxia et al. (2018) Pre-synaptic Muscarinic Excitation Enhances the Discrimination of Looming Stimuli in a Collision-Detection Neuron. Cell Rep 23:2365-2378
Dewell, Richard Burkett; Gabbiani, Fabrizio (2018) Biophysics of object segmentation in a collision-detecting neuron. Elife 7:
Ko, Byung Yi; Xiao, Yangyan; Barbosa, Flavia L et al. (2018) Goblet cell loss abrogates ocular surface immune tolerance. JCI Insight 3:
Shen, Guofu; Link, Schuyler; Kumar, Sandeep et al. (2018) Characterization of Retinal Ganglion Cell and Optic Nerve Phenotypes Caused by Sustained Intracranial Pressure Elevation in Mice. Sci Rep 8:2856

Showing the most recent 10 out of 349 publications