Abstract

The core facilities will maintain and expand the Vision Research Center established in the Department of Ophthalmology at Washington University to provide essential services for faculty members whose research interests are in one or another aspect of vision. The Vision Research Center significantly facilitates the interaction between several investigators and makes it possible for them to advance their ongoing research, most of which is supported by individual research grants from NEI. The current application requests support for one year for a continuing service module (the electronics and machine shops) and a new EM module. Core grant support for one year only is requested, even though this is the time for our fives years competing renewal application, because the department is in a state of transition with the arrival of Dr. Henry Kaplan, as chairman, in April, 1988. Dramatic expansion of the clinical and research faculty will occur in the next 12 months and the configuration of the Core Grant will be significantly different in June, 1989 from that requested in this application (please see Background for details).

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Eye Institute (NEI)
Type
Center Core Grants (P30)
Project #
2P30EY002687-11
Application #
3102540
Study Section
Vision Research and Training Committee (VSN)
Project Start
1978-12-01
Project End
1990-03-31
Budget Start
1989-04-01
Budget End
1990-03-31
Support Year
11
Fiscal Year
1989
Total Cost
Indirect Cost

  Institution

Name
Washington University
Department
Type
Schools of Medicine
DUNS #
062761671
City
Saint Louis
State
MO
Country
United States
Zip Code
63130

  Publications

Kiser, Philip D; Zhang, Jianye; Sharma, Aditya et al. (2018) Retinoid isomerase inhibitors impair but do not block mammalian cone photoreceptor function. J Gen Physiol 150:571-590
Soto, Florentina; Zhao, Lei; Kerschensteiner, Daniel (2018) Synapse maintenance and restoration in the retina by NGL2. Elife 7:
Ban, Norimitsu; Siegfried, Carla J; Apte, Rajendra S (2018) Monitoring Neurodegeneration in Glaucoma: Therapeutic Implications. Trends Mol Med 24:7-17
Ban, Norimitsu; Lee, Tae Jun; Sene, Abdoulaye et al. (2018) Disrupted cholesterol metabolism promotes age-related photoreceptor neurodegeneration. J Lipid Res 59:1414-1423
Buckingham, Erin M; Foley, Maria A; Grose, Charles et al. (2018) Identification of Herpes Zoster-Associated Temporal Arteritis Among Cases of Giant Cell Arteritis. Am J Ophthalmol 187:51-60
Stunkel, Leanne; Kung, Nathan H; Wilson, Bradley et al. (2018) Incidence and Causes of Overdiagnosis of Optic Neuritis. JAMA Ophthalmol 136:76-81
Gordon, Mae O; Kass, Michael A (2018) What We Have Learned From the Ocular Hypertension Treatment Study. Am J Ophthalmol 189:xxiv-xxvii
Andley, Usha P; Tycksen, Eric; McGlasson-Naumann, Brittney N et al. (2018) Probing the changes in gene expression due to ?-crystallin mutations in mouse models of hereditary human cataract. PLoS One 13:e0190817
Vinberg, Frans; Peshenko, Igor V; Chen, Jeannie et al. (2018) Guanylate cyclase-activating protein 2 contributes to phototransduction and light adaptation in mouse cone photoreceptors. J Biol Chem 293:7457-7465
Gordon, Mae O; Higginbotham, Eve J; Heuer, Dale K et al. (2018) Assessment of the Impact of an Endpoint Committee in the Ocular Hypertension Treatment Study. Am J Ophthalmol :

Showing the most recent 10 out of 696 publications