The primary function of the Morphology and Imaging Module is to provide access to expert personnel and equipment for histological studies of ocular tissues. This Module enhances the research environment by providing access to state-of-the-art equipment to those investigators who use anatomical and imaging techniques, and because of the available technical expertise, it allows others to add anatomical techniques into their repertoire of research tools. For example, vision scientists trained in molecular biology or physiology can easily incorporate immunocytochemistry or in situ hybridization techniques into their studies of gene expression. Finally, the Morphology and Imaging Module has promoted pilot projects by providing technical help, which, because of current commitments or lack of experience, is often unavailable in individual laboratories. The latter has led to stronger R01 grant proposals as well as significant publications that otherwise would not have been possible.

Agency
National Institute of Health (NIH)
Institute
National Eye Institute (NEI)
Type
Center Core Grants (P30)
Project #
5P30EY007003-25
Application #
8264346
Study Section
Special Emphasis Panel (ZEY1)
Project Start
Project End
2012-06-30
Budget Start
2011-05-01
Budget End
2012-06-30
Support Year
25
Fiscal Year
2011
Total Cost
$111,720
Indirect Cost
Name
University of Michigan Ann Arbor
Department
Type
DUNS #
073133571
City
Ann Arbor
State
MI
Country
United States
Zip Code
48109
Zhang, Haonan; Xie, Xinyi; Li, Jia et al. (2018) Removal of choroidal vasculature using concurrently applied ultrasound bursts and nanosecond laser pulses. Sci Rep 8:12848
Kiang, Lee; Ross, Bing X; Yao, Jingyu et al. (2018) Vitreous Cytokine Expression and a Murine Model Suggest a Key Role of Microglia in the Inflammatory Response to Retinal Detachment. Invest Ophthalmol Vis Sci 59:3767-3778
Saera-Vila, Alfonso; Louie, Ke'ale W; Sha, Cuilee et al. (2018) Extraocular muscle regeneration in zebrafish requires late signals from Insulin-like growth factors. PLoS One 13:e0192214
Lu, Yan; Atkins, Stephen J; Fernando, Roshini et al. (2018) CD34- Orbital Fibroblasts From Patients With Thyroid-Associated Ophthalmopathy Modulate TNF-? Expression in CD34+ Fibroblasts and Fibrocytes. Invest Ophthalmol Vis Sci 59:2615-2622
Bian, Zong-Mei; Field, Matthew G; Elner, Susan G et al. (2018) Distinct CD40L receptors mediate inflammasome activation and secretion of IL-1? and MCP-1 in cultured human retinal pigment epithelial cells. Exp Eye Res 170:29-39
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Chawla, Bahaar; Swain, William; Williams, Antionette L et al. (2018) Retinoic Acid Maintains Function of Neural Crest-Derived Ocular and Craniofacial Structures in Adult Zebrafish. Invest Ophthalmol Vis Sci 59:1924-1935
Shibata, Maho; Ishizaki, Eisuke; Zhang, Ting et al. (2018) Purinergic Vasotoxicity: Role of the Pore/Oxidant/KATP Channel/Ca2+ Pathway in P2X7-Induced Cell Death in Retinal Capillaries. Vision (Basel) 2:
Lundy, Steven K; Nikoopour, Enayat; Karoukis, Athanasios J et al. (2018) T Helper 1 Cellular Immunity Toward Recoverin Is Enhanced in Patients With Active Autoimmune Retinopathy. Front Med (Lausanne) 5:249
Bian, Zong-Mei; Field, Matthew G; Elner, Susan G et al. (2018) Expression and regulation of alarmin cytokine IL-1? in human retinal pigment epithelial cells. Exp Eye Res 172:10-20

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