PARENT ABSTRACT (CORE ABSTRACT NOT PROVIDED) DESCRIPTION (provided by applicant): This NEI P30 award provides ongoing and stable funding for four high quality and productive vision research service Modules: Instrument Design, Research Computer Programming, Biostatistics and Biological Imaging. These Modules are run by an exceptionally talented staff that has from 2 to 15 years of experience in our Core Center for Vision Research. The Modules provide needed research services to a present group of 23 Core Center vision scientists from 5 departments of the University of Houston (Biochemistry, Biology, Pharmacology, Electrical Engineering, and Optometry). These Core vision scientists have diverse training and research interests, they collaborate effectively with each other, as well as with some 100 other vision researchers at this University and at other institutions. Together, our 23 Core Center investigators have 13 qualifying NEI-funded grants. The College of Optometry and University of Houston provide considerable additional commitments in support of vision research. During the past 5 years of P30 funding at this University, the Core Center has created an unusually favorable vision-research environment that has directly contributed to 138 published papers and culminated in the recruitment of 9 new vision investigators, 7 of whom currently have NIH funding, including 3 who have new NEI funding. These accomplishments reflect our Core Center's previous and current aims that focus on stable funding, quality research services, collaborative research, innovative research, new vision researchers, and new projects converting into NIH and NEI support. Especially emphasized in the coming 5 years will be innovative research (e. g., adaptive optics) and recruitment of vision researchers to fill our current 3 open basic science positions, as well as other positions in the future.

Agency
National Institute of Health (NIH)
Institute
National Eye Institute (NEI)
Type
Center Core Grants (P30)
Project #
2P30EY007551-16
Application #
6721599
Study Section
Project Start
2003-03-01
Project End
2008-02-28
Budget Start
2003-03-01
Budget End
2004-02-29
Support Year
16
Fiscal Year
2003
Total Cost
$126,221
Indirect Cost
Name
University of Houston
Department
Type
DUNS #
036837920
City
Houston
State
TX
Country
United States
Zip Code
77204
Rodarte, Elsa M; Ramos, Marco A; Davalos, Alfredo J et al. (2018) Munc13 proteins control regulated exocytosis in mast cells. J Biol Chem 293:345-358
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Patel, Nimesh; McAllister, Faith; Pardon, Laura et al. (2018) The effects of graded intraocular pressure challenge on the optic nerve head. Exp Eye Res 169:79-90
Hung, Li-Fang; Arumugam, Baskar; Ostrin, Lisa et al. (2018) The Adenosine Receptor Antagonist, 7-Methylxanthine, Alters Emmetropizing Responses in Infant Macaques. Invest Ophthalmol Vis Sci 59:472-486
Gutierrez, Berenice A; Chavez, Miguel A; Rodarte, Alejandro I et al. (2018) Munc18-2, but not Munc18-1 or Munc18-3, controls compound and single-vesicle-regulated exocytosis in mast cells. J Biol Chem 293:7148-7159
Davis, Joshua T; Foster, William J (2018) Substrate Stiffness Influences the Time Dependence of CTGF Protein Expression in Müller Cells. Int Physiol J 1:1

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