The purpose of the Biological Imaging Module is to provide state of the art imaging facilities and support for Core investigators of the University of Houston Center Core for Vision Research who have interests in structural, cellular and molecular aspects of vision research. This module has been highly successful at facilitating and advancing the research capabilities and the innovative vision science of the Core investigators and will work to continue to do so. The module provides a wide range of up-to-date equipment for use by the investigators and their associates, consultations on strategy, or collaboration on projects. The Module provides facilities for tissue preparation, standard light microscopy, confocal microscopy, deconvolution fluorescence microscopy, live cell imaging, transmission electron microscopy (TEM), scanning electron microscopy serial block-face (SEM-SBF) imaging, image analysis, computer-assisted image segmentation and 3-D reconstruction, and Retinal Tomography and Spectral Domain - Optical Coherence Tomography (SD-OCT) for in vivo imaging of small animals. A highly skilled microscopist/histology technologist is available to coordinate use, assist with histology/microscopy and provide training. The Biological Imaging Module is supervised by Alan R. Burns, Ph.D., McDaid-Vision Source Professor of Optometry and Vision science, who has been an NEI-funded investigator in the UH Core, and Module Director since 2008. Dr. Burns has 13 years of experience in corneal research and 40 years of experience as a light and electron microscopist.

Agency
National Institute of Health (NIH)
Institute
National Eye Institute (NEI)
Type
Center Core Grants (P30)
Project #
2P30EY007551-31
Application #
9584813
Study Section
Special Emphasis Panel (ZEY1)
Project Start
Project End
Budget Start
2018-09-01
Budget End
2019-06-30
Support Year
31
Fiscal Year
2018
Total Cost
Indirect Cost
Name
University of Houston
Department
Type
DUNS #
036837920
City
Houston
State
TX
Country
United States
Zip Code
77204
Gutierrez, Berenice A; Chavez, Miguel A; Rodarte, Alejandro I et al. (2018) Munc18-2, but not Munc18-1 or Munc18-3, controls compound and single-vesicle-regulated exocytosis in mast cells. J Biol Chem 293:7148-7159
Davis, Joshua T; Foster, William J (2018) Substrate Stiffness Influences the Time Dependence of CTGF Protein Expression in Müller Cells. Int Physiol J 1:1
Ostrin, Lisa A; Sajjadi, Auzita; Benoit, Julia S (2018) Objectively Measured Light Exposure During School and Summer in Children. Optom Vis Sci 95:332-342
McAllister, Faith; Harwerth, Ronald; Patel, Nimesh (2018) Assessing the True Intraocular Pressure in the Non-human Primate. Optom Vis Sci 95:113-119
Huang, Juan; Lentsch, Matthew J; Marsack, Jason D et al. (2018) Evaluating the use of a temperature sensor to monitor spectacle compliance in warm versus cold climates. Clin Exp Optom :
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Abbott, Kaleb S; Queener, Hope M; Ostrin, Lisa A (2018) The ipRGC-Driven Pupil Response with Light Exposure, Refractive Error, and Sleep. Optom Vis Sci 95:323-331
Vantipalli, Srilatha; Li, Jiasong; Singh, Manmohan et al. (2018) Effects of Thickness on Corneal Biomechanical Properties Using Optical Coherence Elastography. Optom Vis Sci 95:299-308
Ostrin, Lisa A (2018) The ipRGC-driven pupil response with light exposure and refractive error in children. Ophthalmic Physiol Opt 38:503-515
Schulle, Krystal L; Berntsen, David A; Sinnott, Loraine T et al. (2018) Visual Acuity and Over-refraction in Myopic Children Fitted with Soft Multifocal Contact Lenses. Optom Vis Sci 95:292-298

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