The purpose of the Biological Imaging Module is to provide state of the art imaging facilities and support for Core investigators of the University of Houston Center Core for Vision Research who have interests in structural, cellular and molecular aspects of vision research. This module has been highly successful at facilitating and advancing the research capabilities and the innovative vision science of the Core investigators and will work to continue to do so. The module provides a wide range of up-to-date equipment for use by the investigators and their associates, consultations on strategy, or collaboration on projects. The Module provides facilities for tissue preparation, standard light microscopy, confocal microscopy, deconvolution fluorescence microscopy, live cell imaging, transmission electron microscopy (TEM), scanning electron microscopy serial block-face (SEM-SBF) imaging, image analysis, computer-assisted image segmentation and 3-D reconstruction, and Retinal Tomography and Spectral Domain - Optical Coherence Tomography (SD-OCT) for in vivo imaging of small animals. A highly skilled microscopist/histology technologist is available to coordinate use, assist with histology/microscopy and provide training. The Biological Imaging Module is supervised by Alan R. Burns, Ph.D., McDaid-Vision Source Professor of Optometry and Vision science, who has been an NEI-funded investigator in the UH Core, and Module Director since 2008. Dr. Burns has 13 years of experience in corneal research and 40 years of experience as a light and electron microscopist.

Agency
National Institute of Health (NIH)
Institute
National Eye Institute (NEI)
Type
Center Core Grants (P30)
Project #
2P30EY007551-31
Application #
9584813
Study Section
Special Emphasis Panel (ZEY1)
Project Start
Project End
Budget Start
2018-09-01
Budget End
2019-06-30
Support Year
31
Fiscal Year
2018
Total Cost
Indirect Cost
Name
University of Houston
Department
Type
DUNS #
036837920
City
Houston
State
TX
Country
United States
Zip Code
77204
Rodarte, Elsa M; Ramos, Marco A; Davalos, Alfredo J et al. (2018) Munc13 proteins control regulated exocytosis in mast cells. J Biol Chem 293:345-358
Takahata, Toru; Patel, Nimesh B; Balaram, Pooja et al. (2018) Long-term histological changes in the macaque primary visual cortex and the lateral geniculate nucleus after monocular deprivation produced by early restricted retinal lesions and diffuser induced form deprivation. J Comp Neurol 526:2955-2972
Lentsch, Matthew J; Marsack, Jason D; Anderson, Heather A (2018) Objective measurement of spectacle wear with a temperature sensor data logger. Ophthalmic Physiol Opt 38:37-47
Skidmore, Kelsea V; Walker, Maria K; Marsack, Jason D et al. (2018) A measure of tear inflow in habitual scleral lens wearers with and without midday fogging. Cont Lens Anterior Eye :
Hung, Li-Fang; Arumugam, Baskar; She, Zhihui et al. (2018) Narrow-band, long-wavelength lighting promotes hyperopia and retards vision-induced myopia in infant rhesus monkeys. Exp Eye Res 176:147-160
Roberts, Tawna L; Manny, Ruth E; Benoit, Julia S et al. (2018) Impact of Cognitive Demand during Sustained Near Tasks in Children and Adults. Optom Vis Sci 95:223-233
Patel, Nimesh; McAllister, Faith; Pardon, Laura et al. (2018) The effects of graded intraocular pressure challenge on the optic nerve head. Exp Eye Res 169:79-90
Hung, Li-Fang; Arumugam, Baskar; Ostrin, Lisa et al. (2018) The Adenosine Receptor Antagonist, 7-Methylxanthine, Alters Emmetropizing Responses in Infant Macaques. Invest Ophthalmol Vis Sci 59:472-486
Gutierrez, Berenice A; Chavez, Miguel A; Rodarte, Alejandro I et al. (2018) Munc18-2, but not Munc18-1 or Munc18-3, controls compound and single-vesicle-regulated exocytosis in mast cells. J Biol Chem 293:7148-7159
Davis, Joshua T; Foster, William J (2018) Substrate Stiffness Influences the Time Dependence of CTGF Protein Expression in Müller Cells. Int Physiol J 1:1

Showing the most recent 10 out of 468 publications