The purpose of the Biological Imaging Module is to provide state of the art imaging facilities and support for Core investigators of the University of Houston Center Core for Vision Research who have interests in structural, cellular and molecular aspects of vision research. This module has been highly successful at facilitating and advancing the research capabilities and the innovative vision science of the Core investigators and will work to continue to do so. The module provides a wide range of up-to-date equipment for use by the investigators and their associates, consultations on strategy, or collaboration on projects. The Module provides facilities for tissue preparation, standard light microscopy, confocal microscopy, deconvolution fluorescence microscopy, live cell imaging, transmission electron microscopy (TEM), scanning electron microscopy serial block-face (SEM-SBF) imaging, image analysis, computer-assisted image segmentation and 3-D reconstruction, and Retinal Tomography and Spectral Domain - Optical Coherence Tomography (SD-OCT) for in vivo imaging of small animals. A highly skilled microscopist/histology technologist is available to coordinate use, assist with histology/microscopy and provide training. The Biological Imaging Module is supervised by Alan R. Burns, Ph.D., McDaid-Vision Source Professor of Optometry and Vision science, who has been an NEI-funded investigator in the UH Core, and Module Director since 2008. Dr. Burns has 13 years of experience in corneal research and 40 years of experience as a light and electron microscopist.

Agency
National Institute of Health (NIH)
Institute
National Eye Institute (NEI)
Type
Center Core Grants (P30)
Project #
5P30EY007551-33
Application #
9968275
Study Section
Special Emphasis Panel (ZEY1)
Project Start
Project End
Budget Start
2020-07-01
Budget End
2021-06-30
Support Year
33
Fiscal Year
2020
Total Cost
Indirect Cost
Name
University of Houston
Department
Type
DUNS #
036837920
City
Houston
State
TX
Country
United States
Zip Code
77204
Jnawali, Ashutosh; Beach, Krista M; Ostrin, Lisa A (2018) In Vivo Imaging of the Retina, Choroid, and Optic Nerve Head in Guinea Pigs. Curr Eye Res 43:1006-1018
Abbott, Kaleb S; Queener, Hope M; Ostrin, Lisa A (2018) The ipRGC-Driven Pupil Response with Light Exposure, Refractive Error, and Sleep. Optom Vis Sci 95:323-331
Vantipalli, Srilatha; Li, Jiasong; Singh, Manmohan et al. (2018) Effects of Thickness on Corneal Biomechanical Properties Using Optical Coherence Elastography. Optom Vis Sci 95:299-308
Ostrin, Lisa A (2018) The ipRGC-driven pupil response with light exposure and refractive error in children. Ophthalmic Physiol Opt 38:503-515
Schulle, Krystal L; Berntsen, David A; Sinnott, Loraine T et al. (2018) Visual Acuity and Over-refraction in Myopic Children Fitted with Soft Multifocal Contact Lenses. Optom Vis Sci 95:292-298
Roberts, Tawna L; Stevenson, Scott B; Benoit, Julia S et al. (2018) Blur Detection, Depth of Field, and Accommodation in Emmetropic and Hyperopic Children. Optom Vis Sci 95:212-222
Rodarte, Elsa M; Ramos, Marco A; Davalos, Alfredo J et al. (2018) Munc13 proteins control regulated exocytosis in mast cells. J Biol Chem 293:345-358
Takahata, Toru; Patel, Nimesh B; Balaram, Pooja et al. (2018) Long-term histological changes in the macaque primary visual cortex and the lateral geniculate nucleus after monocular deprivation produced by early restricted retinal lesions and diffuser induced form deprivation. J Comp Neurol 526:2955-2972
Lentsch, Matthew J; Marsack, Jason D; Anderson, Heather A (2018) Objective measurement of spectacle wear with a temperature sensor data logger. Ophthalmic Physiol Opt 38:37-47
Skidmore, Kelsea V; Walker, Maria K; Marsack, Jason D et al. (2018) A measure of tear inflow in habitual scleral lens wearers with and without midday fogging. Cont Lens Anterior Eye :

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