The Vanderbilt Vision Research Center (WRC) includes faculty in the College of Arts &Science, Peabody College of Education, School of Engineering and School of Medicine. The high level of performance of WRC researchers derived from Core grant support also synergizes with campus-wide investments in biomedical research and training at Vanderbilt. We request continued support for five cores. (1) The Animal Care Core provides specialized surgical support and veterinary care of nonhuman primates and other large animals and murine electroretinogram phenotyping. (2) The Computer Core provides hardware installation and maintenance, software development for visual displays and real-time data acquisition and analysis, and webpage maintenance and data acquisition. (3) The Imaging Core facilitates acquisition and analysis of functional brain imaging, optical imaging, confocal and standard microscopy and other imaging data. (4) The Gene &Protein Analysis Core provides timely and economical access to genomic, proteomic and histology services. (5) The Shop Core designs, fabricates and repairs specialized optical, mechanical and electronic instruments. Administrative support ensures continued smooth and stable operation of the WRC research and training missions. Cores are directed by investigators with history of NEI funding, have talented and experienced staff and provide services that are otherwise not available or would be prohibitively expensive or slow. During the last grant period more than three NEI-funded investigators used each core at least moderately. WRC investigators produced five hundred publications that made fundamental contributions to basic and clinical visual science. This Core grant has increased collaborations within and between basic and clinical vision researchers across the Vanderbilt campus and with other institutions. This Core grant has enhanced recruitment of world-class eye and vision researchers resulting in continued extensive NEI-sponsored research at Vanderbilt. PUBLICH

Public Health Relevance

The research facilitated by this Core grant seeks to improve our understanding of the eye and visual system in normal and diseased states. This knowledge will be used to improve the diagnosis and treatment of visual impairments.

Agency
National Institute of Health (NIH)
Institute
National Eye Institute (NEI)
Type
Center Core Grants (P30)
Project #
2P30EY008126-26
Application #
8745029
Study Section
Special Emphasis Panel (ZEY1)
Program Officer
Liberman, Ellen S
Project Start
1997-04-01
Project End
2019-06-30
Budget Start
2014-09-01
Budget End
2015-06-30
Support Year
26
Fiscal Year
2014
Total Cost
Indirect Cost
Name
Vanderbilt University Medical Center
Department
Ophthalmology
Type
Schools of Medicine
DUNS #
City
Nashville
State
TN
Country
United States
Zip Code
37212
Covington, Brett C; Spraggins, Jeffrey M; Ynigez-Gutierrez, Audrey E et al. (2018) Response of Hypogean Actinobacterial Genera Secondary Metabolism to Chemical and Biological Stimuli. Appl Environ Microbiol :
Lu, Sichang; McGough, Madison A P; Shiels, Stefanie M et al. (2018) Settable polymer/ceramic composite bone grafts stabilize weight-bearing tibial plateau slot defects and integrate with host bone in an ovine model. Biomaterials 179:29-45
Wareham, Lauren K; Buys, Emmanuel S; Sappington, Rebecca M (2018) The nitric oxide-guanylate cyclase pathway and glaucoma. Nitric Oxide 77:75-87
Cosman, Joshua D; Lowe, Kaleb A; Zinke, Wolf et al. (2018) Prefrontal Control of Visual Distraction. Curr Biol 28:414-420.e3
Friedrich, Michael G; Wang, Zhen; Schey, Kevin L et al. (2018) DehydroalanylGly, a new post translational modification resulting from the breakdown of glutathione. Biochim Biophys Acta Gen Subj 1862:907-913
Keefe, Jonathan M; Sy, Jocelyn L; Tong, Frank et al. (2018) The emotional attentional blink is robust to divided attention. Atten Percept Psychophys :
Kook, Seunghyi; Qi, Aidong; Wang, Ping et al. (2018) Gene-edited MLE-15 Cells as a Model for the Hermansky-Pudlak Syndromes. Am J Respir Cell Mol Biol 58:566-574
Kovtun, Oleg; Tomlinson, Ian D; Bailey, Danielle M et al. (2018) Single Quantum Dot Tracking Illuminates Neuroscience at the Nanoscale. Chem Phys Lett 706:741-752
Wang, Zhen; Schey, Kevin L (2018) Proteomic Analysis of S-Palmitoylated Proteins in Ocular Lens Reveals Palmitoylation of AQP5 and MP20. Invest Ophthalmol Vis Sci 59:5648-5658
Fougnie, Daryl; Cockhren, Jurnell; Marois, René (2018) A common source of attention for auditory and visual tracking. Atten Percept Psychophys 80:1571-1583

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