Bascom Palmer Eye Institute (BPEI) is a comprehensive, disease-focused academic unit that serves as the Department of Ophthalmology for the University of Miami Miller School of Medicine. The Anne Bates Leach Eye Center is Bascom Palmer's main facility for ophthalmic care. The adjacent Evelyn F. and William L. McKnight Vision Research Center (MVRC) is BPEI's research arm, and also coordinates all aspects of BPEI's research mission. Moreover, MVRC draws together NEI-funded eye and vision research investigators across the University of Miami and nearby institutions as the Miami Eye Team. This P30 core center grant application is specifically directed towards this group of investigators to sustain their activities, foster interdisciplinary research, share core resources and educational programs, and promote research of early stage investigators. The long-term goal of this P30 proposal is to strengthen the conceptual and methodological capabilities of Miami Eye Team investigators, thus expanding and enhancing their contributions to knowledge and understanding of the eye, vision, and blinding eye diseases. We request continued funding of the P30EY014801 Core Grant for Vision Research to support the following core resource modules: (1) Shared Equipment, (2) Experimental Models, (3) Biological Imaging, and partially (4) Biostatistics (10%). The requested modules are configured to add overall scientific value to the vision research environment at the University of Miami by providing for critical needs of the Miami Eye Team investigators. Each module is devoted to specific activities that would be impractical or less efficient for our PIs to support in their individual laboratories, or on NEI research project grants. The importance of these modules to Miami Eye Team investigators is reflected in the quantity and quality of publications including numerous collaborations, NEI submissions and awards over the funding period, and recruitment of new faculty and staff. The Bascom Palmer Eye Institute and the University of Miami are strongly committed to support vision research with significant, continuous financial support to the development and operation of state-of-the art core modules.

Public Health Relevance

This P30 grant, and the modules that it supports, is essential for accomplishing these aims by providing core services and resources for the research activities, an excellent research training environment for faculty, post- doctoral fellows, students, and staff, and allows growth in new research areas, including Metabolomics and stem cell biology.

Agency
National Institute of Health (NIH)
Institute
National Eye Institute (NEI)
Type
Center Core Grants (P30)
Project #
2P30EY014801-16
Application #
9795621
Study Section
Special Emphasis Panel (ZEY1)
Program Officer
Liberman, Ellen S
Project Start
2004-05-01
Project End
2020-08-31
Budget Start
2019-09-01
Budget End
2020-08-31
Support Year
16
Fiscal Year
2019
Total Cost
Indirect Cost
Name
University of Miami School of Medicine
Department
Ophthalmology
Type
Schools of Medicine
DUNS #
052780918
City
Coral Gables
State
FL
Country
United States
Zip Code
33146
Iglesias, Eugenia; Sajnani, Ravin; Levitt, Roy C et al. (2018) Epidemiology of Persistent Dry Eye-Like Symptoms After Cataract Surgery. Cornea 37:893-898
Kovach, Jaclyn L (2018) Extensive Macular Atrophy with Pseudodrusen Imaged with OCT Angiography. Case Rep Ophthalmol Med 2018:8213097
Chang, Victoria S; Rose, Terri P; Karp, Carol L et al. (2018) Neuropathic-Like Ocular Pain and Nonocular Comorbidities Correlate With Dry Eye Symptoms. Eye Contact Lens 44 Suppl 2:S307-S313
Shao, Yilei; Tao, Aizhu; Jiang, Hong et al. (2018) Long scan depth optical coherence tomography on imaging accommodation: impact of enhanced axial resolution, signal-to-noise ratio and speed. Eye Vis (Lond) 5:16
Guo, Ying; Yang, Hui; Chen, Shi et al. (2018) Reduced BAP1 activity prevents ASXL1 truncation-driven myeloid malignancy in vivo. Leukemia 32:1834-1837
Lu, Jianmin; Luo, Lingyu; Huang, Deqiang et al. (2018) Photoreceptor Protection by Mesencephalic Astrocyte-Derived Neurotrophic Factor (MANF). eNeuro 5:
Batawi, Hatim; Lollett, Ivonne Valentina; Maliakal, Cima et al. (2018) A Comparative Study of Central Corneal Epithelial, Stromal, and Total Thickness in Males With and Without Primary Open-Angle Glaucoma. Cornea 37:712-719
Smith, Christopher; Kaitis, Daniel; Winegar, Jordan et al. (2018) Comparison of endothelial/Descemet's membrane complex thickness with endothelial cell density for the diagnosis of corneal transplant rejection. Ther Adv Ophthalmol 10:2515841418814187
Willebrords, Joost; Maes, Michaƫl; Pereira, Isabel Veloso Alves et al. (2018) Protective effect of genetic deletion of pannexin1 in experimental mouse models of acute and chronic liver disease. Biochim Biophys Acta Mol Basis Dis 1864:819-830
Mercado, Carolina L; Pole, Cameron; Wong, James et al. (2018) Surgical versus medical treatment for ocular surface squamous neoplasia: A quality of life comparison. Ocul Surf :

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