Abstract

Tissue Processing and Histology Core The Tissue Processing and Histology Core will continue to serve the needs of UCSD vision researchers by providing dedicated tissue processing equipment and a full-time histotechnician experienced in eye histology and immunohistochemistry. The Tissue Processing and Histology core supports both paraffin and cryosection processing and various staining strategies. The core also provides vision researchers with 1) advice for fixation selection depending on study purpose; 2) paraffin and cryo blocking of study samples; 3) paraffin or cryo histology slide preparation with customized staining, 4) assistance for proper interpretation and precision microsampling of the region of interest for electron microscopy evaluation and 5) high content confocal imaging for drug screening and histologic specimen imaging.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Eye Institute (NEI)
Type
Center Core Grants (P30)
Project #
2P30EY022589-06A1
Application #
9573255
Study Section
Special Emphasis Panel (ZEY1)
Project Start
2018-09-01
Project End
2023-06-30
Budget Start
2018-08-01
Budget End
2019-06-30
Support Year
6
Fiscal Year
2018
Total Cost
Indirect Cost

  Institution

Name
University of California, San Diego
Department
Type
DUNS #
804355790
City
La Jolla
State
CA
Country
United States
Zip Code
92093

  Publications

Muftuoglu, Ilkay Kilic; Gaber, Raouf; Bartsch, Dirk-Uwe et al. (2018) Comparison of conventional color fundus photography and multicolor imaging in choroidal or retinal lesions. Graefes Arch Clin Exp Ophthalmol 256:643-649
Branham, Kari; Guru, Aditya A; Kozak, Igor et al. (2018) Identification of Novel Deletions as the Underlying Cause of Retinal Degeneration in Two Pedigrees. Adv Exp Med Biol 1074:229-236
Christopher, Mark; Belghith, Akram; Weinreb, Robert N et al. (2018) Retinal Nerve Fiber Layer Features Identified by Unsupervised Machine Learning on Optical Coherence Tomography Scans Predict Glaucoma Progression. Invest Ophthalmol Vis Sci 59:2748-2756
Kroeger, Heike; Grimsey, Neil; Paxman, Ryan et al. (2018) The unfolded protein response regulator ATF6 promotes mesodermal differentiation. Sci Signal 11:
Christopher, Mark; Belghith, Akram; Bowd, Christopher et al. (2018) Performance of Deep Learning Architectures and Transfer Learning for Detecting Glaucomatous Optic Neuropathy in Fundus Photographs. Sci Rep 8:16685
You, Qi Sheng; Gaber, Raouf; Meshi, Amit et al. (2018) HIGH-DOSE HIGH-FREQUENCY AFLIBERCEPT FOR RECALCITRANT NEOVASCULAR AGE-RELATED MACULAR DEGENERATION. Retina 38:1156-1165
Bowd, Christopher; Zangwill, Linda M; Weinreb, Robert N et al. (2018) Racial Differences in Rate of Change of Spectral-Domain Optical Coherence Tomography-Measured Minimum Rim Width and Retinal Nerve Fiber Layer Thickness. Am J Ophthalmol 196:154-164
Ju, Won-Kyu; Shim, Myoung Sup; Kim, Keun-Young et al. (2018) Ubiquinol promotes retinal ganglion cell survival and blocks the apoptotic pathway in ischemic retinal degeneration. Biochem Biophys Res Commun 503:2639-2645
Chekuri, Anil; Guru, Aditya A; Biswas, Pooja et al. (2018) IFT88 mutations identified in individuals with non-syndromic recessive retinal degeneration result in abnormal ciliogenesis. Hum Genet 137:447-458
Hou, Huiyuan; Moghimi, Sasan; Zangwill, Linda M et al. (2018) Inter-eye Asymmetry of Optical Coherence Tomography Angiography Vessel Density in Bilateral Glaucoma, Glaucoma Suspect, and Healthy Eyes. Am J Ophthalmol 190:69-77

Showing the most recent 10 out of 266 publications