Abstract

To meet a critical need on the NDSU campus to support and retain an emerging group of biomedical scientists, the Center for Protease Research COBRE program will establish a Pilot Project Program in interdisciplinary biomedical studies. The purpose ofthe program will be to develop interdisciplinary biomedical research in order that the Pis will be more competitive for extramural funding at the R01 level. The project will be funded at $250,000 per year of the 5-year grant period. Following an annual call for competitive proposals, an external grant review committee, the Internal Advisory Board, and the Pilot Project Program Director will critically evaluate projects. Upon consultation with the External Advisory Committee, pilot projects of one- or two-year duration will be prioritized and awarded based on merit, interdisciplinary, and ability to generate preliminary data for an NIH R01 application. Research pilot grant investigators will receive mentoring and guidance through the Center in the writing of required extramural grant proposals, as well as formal and informal mentoring through science seminars and presentations offered by the Center.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Center Core Grants (P30)
Project #
5P30GM103332-03
Application #
8701307
Study Section
Special Emphasis Panel (ZRR1-RI-B)
Project Start
Project End
Budget Start
2014-07-01
Budget End
2015-06-30
Support Year
3
Fiscal Year
2014
Total Cost
$362,500
Indirect Cost
$112,500

  Institution

Name
North Dakota State University
Department
Type
DUNS #
803882299
City
Fargo
State
ND
Country
United States
Zip Code
58108

  Publications

Ambhore, Nilesh Sudhakar; Katragadda, Rathnavali; Raju Kalidhindi, Rama Satyanarayana et al. (2018) Estrogen receptor beta signaling inhibits PDGF induced human airway smooth muscle proliferation. Mol Cell Endocrinol 476:37-47
Mohammad, Jiyan; Dhillon, Harsharan; Chikara, Shireen et al. (2018) Piperlongumine potentiates the effects of gemcitabine in in vitro and in vivo human pancreatic cancer models. Oncotarget 9:10457-10469
Froberg, James; Choi, Woo-Sik; Sedigh, Abbas et al. (2018) Real-time tracking of single-molecule collagenase on native collagen and partially structured collagen-mimic substrates. Chem Commun (Camb) 54:10248-10251
Lundquist, Taylor A; Kittilson, Jeffrey D; Ahsan, Rubina et al. (2018) The effect of within-instar development on tracheal diameter and hypoxia-inducible factors ? and ? in the tobacco hornworm, Manduca sexta. J Insect Physiol 106:199-208
Chikara, Shireen; Mamidi, Sujan; Sreedasyam, Avinash et al. (2018) Flaxseed Consumption Inhibits Chemically Induced Lung Tumorigenesis and Modulates Expression of Phase II Enzymes and Inflammatory Cytokines in A/J Mice. Cancer Prev Res (Phila) 11:27-37
Jensen, Jaime L; Wu, Qiong; Colbert, Christopher L (2018) NMR assignments of the N-terminal signaling domain of the TonB-dependent outer membrane transducer PupB. Biomol NMR Assign 12:91-94
Karandish, Fataneh; Froberg, James; Borowicz, Pawel et al. (2018) Peptide-targeted, stimuli-responsive polymersomes for delivering a cancer stemness inhibitor to cancer stem cell microtumors. Colloids Surf B Biointerfaces 163:225-235
You, Seungyong; Froberg, James; Yu, Junru et al. (2017) Real-time monitoring of conformational transitions of single-molecule histone deacetylase 8 with nanocircuits. Chem Commun (Camb) 53:3307-3310
Vasam, Goutham; Joshi, Shrinidh; Thatcher, Sean E et al. (2017) Reversal of Bone Marrow Mobilopathy and Enhanced Vascular Repair by Angiotensin-(1-7) in Diabetes. Diabetes 66:505-518
Eklund, Bridget E; Mahdi, Osama; Huntley, Jason F et al. (2017) The orange spotted cockroach (Blaptica dubia, Serville 1839) is a permissive experimental host forFrancisella tularensis. Proc W Va Acad Sci 89:34-47

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