The Pilot Project Program (PPP) for the Center for Evolutionary and Theoretical Immunology (CETI) was established in Phase II of CETI's existence. This program, which has proven to be popular in these difficult funding times, is designed to enable investigators to collect data needed to increase the competitiveness of their grants for funding. In so doing, it helps CETI to achieve one of the major goals of the IDeA program, namely to increase our critical mass of funded investigators. The PPP we propose for Phase III has three major goals. The first is to facilitate maintenance of the PPP into Phase III and beyond. We intend to award each successful applicant an amount of $25-50K per annum with the possibility of continued funding into a second year. Because of the need to purchase equipment for our scientific cores, our PPP will be relatively small in years one and two but will be expanded to the full allowable amount in years three through five. Additionally, support received from the UNM administration will provide another $200K to continue our PPP in the five years following Phase III. The second goal of the PPP is to assist our three scientific cores in transitioning to independence from COBRE funding. Beginning in year three, we will begin a phased reduction of COBRE support for each of our three cores. By year five, the cores will be cost neutral. However, funds coming into each core from PPP recipients will help each core achieve cost neutrality. In addition, both our PPP and our waiver program will have the benefit of increasing the user base for each of our scientific cores. A third goal of our PPP is to provide both training for all equipment items used by recipients in our cores, and the mentoring services provided by our Administrative Core. Training will allow recipients to take full advantage of the instrumentation and services in our Cores. Mentoring will emphasize production of more competitive research proposals and favor the long-term academic success of our recipients. Additionally and importantly, PPP recipients will be offered the benefit of using CETI's wellestablished grant preparation and submission portal, thereby greatly facilitating what can be a difficult and demanding process. Finally, all PP recipients will be encouraged to participate in all CETI's programmatic activities, including lunches, seminars, and meetings. The PPP is a vital part of CETI as it increases our core user base and the competitiveness of our investigators, and helps us realize the long-term goals of both CETI and the IDeA program.

Public Health Relevance

In these difficult funding times, the Pilot Project Program overseen by the Administrative Core of the Center for Evolutionary and Theoretical Immunology (CETI) provides much needed funds for investigators, especially beginning investigators, to collect preliminary data needed to support successful full-scale extramural research proposals. By favoring the long-term success of New Mexico scientists, CETI helps improve the economic outlook and scientific competitiveness of our state, in line with the goals of the IDeA program.

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Center Core Grants (P30)
Project #
1P30GM110907-01
Application #
8751182
Study Section
Special Emphasis Panel (ZGM1-TWD-C (3C))
Project Start
Project End
Budget Start
2014-06-01
Budget End
2015-03-31
Support Year
1
Fiscal Year
2014
Total Cost
$75,500
Indirect Cost
$25,500
Name
University of New Mexico
Department
Type
DUNS #
868853094
City
Albuquerque
State
NM
Country
United States
Zip Code
87131
Tasnim, Humayra; Fricke, G Matthew; Byrum, Janie R et al. (2018) Quantitative Measurement of Naïve T Cell Association With Dendritic Cells, FRCs, and Blood Vessels in Lymph Nodes. Front Immunol 9:1571
Ebbs, Erika T; Loker, Eric S; Brant, Sara V (2018) Phylogeography and genetics of the globally invasive snail Physa acuta Draparnaud 1805, and its potential to serve as an intermediate host to larval digenetic trematodes. BMC Evol Biol 18:103
Zhang, Si-Ming; Bu, Lijing; Laidemitt, Martina R et al. (2018) Complete mitochondrial and rDNA complex sequences of important vector species of Biomphalaria, obligatory hosts of the human-infecting blood fluke, Schistosoma mansoni. Sci Rep 8:7341
Ziegler, Maren; Stone, Elizabeth; Colman, Daniel et al. (2018) Patterns of Symbiodinium (Dinophyceae) diversity and assemblages among diverse hosts and the coral reef environment of Lizard Island, Australia. J Phycol 54:447-460
Kelly, Cecelia; Salinas, Irene (2017) Under Pressure: Interactions between Commensal Microbiota and the Teleost Immune System. Front Immunol 8:559
Chan, John D; Cupit, Pauline M; Gunaratne, Gihan S et al. (2017) The anthelmintic praziquantel is a human serotoninergic G-protein-coupled receptor ligand. Nat Commun 8:1910
Sepahi, Ali; Tacchi, Luca; Casadei, Elisa et al. (2017) CK12a, a CCL19-like Chemokine That Orchestrates both Nasal and Systemic Antiviral Immune Responses in Rainbow Trout. J Immunol 199:3900-3913
Lovato, TyAnna L; Cripps, Richard M (2017) High Heart: A Role for Calcineurin Signaling in Hypoxia-Influenced Cardiac Growth. Circ Cardiovasc Genet 10:
Buddenborg, Sarah K; Bu, Lijing; Zhang, Si-Ming et al. (2017) Transcriptomic responses of Biomphalaria pfeifferi to Schistosoma mansoni: Investigation of a neglected African snail that supports more S. mansoni transmission than any other snail species. PLoS Negl Trop Dis 11:e0005984
Mrass, Paulus; Oruganti, Sreenivasa Rao; Fricke, G Matthew et al. (2017) ROCK regulates the intermittent mode of interstitial T cell migration in inflamed lungs. Nat Commun 8:1010

Showing the most recent 10 out of 91 publications