The ability to view, measure and record characteristics of biological samples or organismal behavior? lies at the heart of scientific investigation. The overall objective of the Integrative Imaging Core (IIC)? is to utilize skilled and knowledgeable staff to apply state-of-the-art imaging technology to? MRDDRC research programs.? Imaging technology is pervasive throughout biomedical investigation. Contemporary high-throughput? gene expression analysis relies on the ability to image microarrays with laser scanners, and this is? frequently combined with imaging technology used to isolate single cells or homogeneous cell? populations. Microscopic imaging of cells or tissues after any number of staining procedures provides? valuable information on cell phenotype and tissue organization. Whole animal imaging by video? recording of behavioral activity or magnetic resonance imaging of internal structure provides new? insight into the structure and function of the central nervous system. Frequently, research problems no? longer rely on any single technology, but more often multiple integrative approaches are brought to? bear to achieve a solution.? Research productivity often is limited by how well investigators are able to incorporate into their? programs these specialized technologies, with their steep learning curves and sophisticated and costly? equipment. The central goal of the Integrative Imaging Core is to make accessible to MRDDRC? investigators new research tools that rely on imaging technology by providing 1) access to appropriate? instrumentation, 2) skilled staff to conduct imaging-based services for investigators and to train? investigators to use imaging-based instruments, and 3) to provide support where appropriate to ensure? that image-based data are of the highest possible standard. These Core activities ensure that research? productivity and quality remain of the highest caliber, and present researchers with new opportunities? for investigation and collaboration.
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