This Core, renamed from the Design and Statistical Computing Core to the Data Management and StatisticalAnalysis (DMSA) Core, has been part of the UNC Mental Retardation Research Center since 1987, and nowalso includes access to expertise related to the microarray gene expression added to the UNC DDRC in 2003.The overall objectives of the DMSA Core are to enhance the productivity of UNC DDRC investigators and toenhance the quality of their research. We achieve these objectives by collaborating with investigators,providing them with services through every stage of a research project. We participate in writing grantproposals, developing efficient experimental designs, designing data collection instruments, conducting pilottests, designing and implementing database management systems, supervising execution of the study andcollection of data, operating database management systems to clean, store, and retrieve data, performingstatistical analyses, writing research papers and reports, and archiving databases. To each phase of theresearch effort we contribute the unique perspectives and experiences of psychometricians, biostatisticians,professionally trained research database managers, and a support staff of proficient programmers and datamanagers. Our efforts regarding both traditional data management and analysis and bioinformatics have beenintegrated into the UNC DDRC. Drs. Burchinal, Gu, Poe, and Zu have been consistent co-authors inpublication and Drs. Burchinal, Wright, Gu, Poe, and Neebe have been co-investigators on UNC DDRCprojects.

Agency
National Institute of Health (NIH)
Institute
Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD)
Type
Center Core Grants (P30)
Project #
2P30HD003110-41
Application #
7563413
Study Section
Special Emphasis Panel (ZHD1-MRG-C (12))
Project Start
1997-08-01
Project End
2013-06-30
Budget Start
2008-08-01
Budget End
2009-06-30
Support Year
41
Fiscal Year
2008
Total Cost
$212,554
Indirect Cost
Name
University of North Carolina Chapel Hill
Department
Type
DUNS #
608195277
City
Chapel Hill
State
NC
Country
United States
Zip Code
27599
Lyu, Ilwoo; Kim, Sun Hyung; Girault, Jessica B et al. (2018) A cortical shape-adaptive approach to local gyrification index. Med Image Anal 48:244-258
Klusek, Jessica; Ruber, Alexis; Roberts, Jane E (2018) Impaired eye contact in the FMR1 premutation is not associated with social anxiety or the broad autism phenotype. Clin Neuropsychol 32:1337-1352
Harrop, Clare; Jones, Desiree; Zheng, Shuting et al. (2018) Circumscribed Interests and Attention in Autism: The Role of Biological Sex. J Autism Dev Disord 48:3449-3459
Tu, Liyun; Styner, Martin; Vicory, Jared et al. (2018) Skeletal Shape Correspondence Through Entropy. IEEE Trans Med Imaging 37:1-11
Laxman, D J; Greenberg, J S; DaWalt, L S et al. (2018) Medication use by adolescents and adults with fragile X syndrome. J Intellect Disabil Res 62:94-105
Lyu, Ilwoo; Perdomo, Jonathan; Yapuncich, Gabriel S et al. (2018) Group-wise Shape Correspondence of Variable and Complex Objects. Proc SPIE Int Soc Opt Eng 10574:
Nowell, Sallie W; Watson, Linda R; Faldowski, Richard A et al. (2018) An Initial Psychometric Evaluation of the Joint Attention Protocol. J Autism Dev Disord 48:1932-1944
Jha, Shaili C; Xia, Kai; Schmitt, James Eric et al. (2018) Genetic influences on neonatal cortical thickness and surface area. Hum Brain Mapp 39:4998-5013
Barstein, Jamie; Martin, Gary E; Lee, Michelle et al. (2018) A Duck Wearing Boots?! Pragmatic Language Strategies for Repairing Communication Breakdowns Across Genetically Based Neurodevelopmental Disabilities. J Speech Lang Hear Res 61:1440-1454
Woodbury-Smith, Marc; Paterson, Andrew D; O'Connor, Irene et al. (2018) A genome-wide linkage study of autism spectrum disorder and the broad autism phenotype in extended pedigrees. J Neurodev Disord 10:20

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