This Core, renamed from the Design and Statistical Computing Core to the Data Management and Statistical Analysis (DMSA) Core, has been part of the UNC Mental Retardation Research Center since 1987, and now also includes access to expertise related to the microarray gene expression added to the UNC DDRC in 2003. The overall objectives of the DMSA Core are to enhance the productivity of UNC DDRC investigators and to enhance the quality of their research. We achieve these objectives by collaborating with investigators, providing them with services through every stage of a research project. We participate in writing grant proposals, developing efficient experimental designs, designing data collection instruments, conducting pilot tests, designing and implementing database management systems, supervising execution of the study and collection of data, operating database management systems to clean, store, and retrieve data, performing statistical analyses, writing research papers and reports, and archiving databases. To each phase of the research effort we contribute the unique perspectives and experiences of psychometricians, biostatisticians, professionally trained research database managers, and a support staff of proficient programmers and data managers. Our efforts regarding both traditional data management and analysis and bioinformatics have been integrated into the UNC DDRC. Drs. Burchinal, Gu, Poe, and Zu have been consistent co-authors in publication and Drs. Burchinal, Wright, Gu, Poe, and Neebe have been co-investigators on UNC DDRC projects.

National Institute of Health (NIH)
Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD)
Center Core Grants (P30)
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Special Emphasis Panel (ZHD1-MRG-C)
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University of North Carolina Chapel Hill
Chapel Hill
United States
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Lyu, Ilwoo; Kim, Sun Hyung; Girault, Jessica B et al. (2018) A cortical shape-adaptive approach to local gyrification index. Med Image Anal 48:244-258
Klusek, Jessica; Ruber, Alexis; Roberts, Jane E (2018) Impaired eye contact in the FMR1 premutation is not associated with social anxiety or the broad autism phenotype. Clin Neuropsychol 32:1337-1352
Harrop, Clare; Jones, Desiree; Zheng, Shuting et al. (2018) Circumscribed Interests and Attention in Autism: The Role of Biological Sex. J Autism Dev Disord 48:3449-3459
Tu, Liyun; Styner, Martin; Vicory, Jared et al. (2018) Skeletal Shape Correspondence Through Entropy. IEEE Trans Med Imaging 37:1-11
Laxman, D J; Greenberg, J S; DaWalt, L S et al. (2018) Medication use by adolescents and adults with fragile X syndrome. J Intellect Disabil Res 62:94-105
Lyu, Ilwoo; Perdomo, Jonathan; Yapuncich, Gabriel S et al. (2018) Group-wise Shape Correspondence of Variable and Complex Objects. Proc SPIE Int Soc Opt Eng 10574:
Nowell, Sallie W; Watson, Linda R; Faldowski, Richard A et al. (2018) An Initial Psychometric Evaluation of the Joint Attention Protocol. J Autism Dev Disord 48:1932-1944
Jha, Shaili C; Xia, Kai; Schmitt, James Eric et al. (2018) Genetic influences on neonatal cortical thickness and surface area. Hum Brain Mapp 39:4998-5013
Barstein, Jamie; Martin, Gary E; Lee, Michelle et al. (2018) A Duck Wearing Boots?! Pragmatic Language Strategies for Repairing Communication Breakdowns Across Genetically Based Neurodevelopmental Disabilities. J Speech Lang Hear Res 61:1440-1454
Woodbury-Smith, Marc; Paterson, Andrew D; O'Connor, Irene et al. (2018) A genome-wide linkage study of autism spectrum disorder and the broad autism phenotype in extended pedigrees. J Neurodev Disord 10:20

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