We seek continued support for the Waisman Intellectual and Developmental Disabilities Research Center, a comprehensive interdisciplinary program on IDD spanning the biological, biobehavioral, and behavioral sciences. The Waisman IDDRC brings together 49 PIs from 25 academic departments from the UW-Madison Schools of Medicine and Public Health, Veterinary Medicine, Pharmacy, Agriculture and Life Sciences, Letters and Science, Education, and Human Ecology. This application requests support for an Administrative Core (Core A), providing scientific leadership, program and faculty development, facilitation of interdisciplinary collaboration, and biostatistical and bioinformatics expertise;ad four innovative scientific core services: Research Participation (Core B), providing services, resources, and training in the recruitment of human participants, clinical assessment, and behavioral methods development;Brain Imaging (Core C), providing access to state-of-the-art neuroimaging instrumentation (3T MRI, PET, and microPET scanners for human, non-human primate, and rodent scanning, and an EEG recording system), as well as expertise and tools for image acquisition and analysis;Rodent Models (Core D), providing resources, expertise, and technical services in the generation, cryopreservation, and maintenance of mutant or genetically engineered strains of mice, and advanced behavioral testing facilities for phenotypic characterization;and Cellular and Molecular Neuroscience (Core E), providing cellular and molecular neuroscience technology, training, and expertise, and supporting the generation of iPS cell lines from humans with IDD conditions. We propose to provide core support to 95 research projects headed by 49 PIs organized into three research groups: Molecular and Genetic Sciences, Communicative and Cognitive Sciences, and Social and Affective Sciences. Collectively, the core services and research groups of the Waisman Center IDDRC will stimulate new interdisciplinary IDD research and enhance existing IDD investigations, sharpening our focus on discovery, prevention, and treatment for IDD conditions and improvement of the quality of life of individuals with IDD and their families.

Public Health Relevance

The mission of the Waisman IDDRC is to promote the highest level of IDD research by providing access to cutting-edge and efficient core services, seminars, and pre- and post-doctoral training via a comprehensive program designed to produce a transformative understanding of IDD pathology, development of new therapies, and training the next generation of basic and clinical IDD researchers.

National Institute of Health (NIH)
Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD)
Center Core Grants (P30)
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Special Emphasis Panel (ZHD1)
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Parisi, Melissa
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University of Wisconsin Madison
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United States
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Song, Jieun; Mailick, Marsha R; Greenberg, Jan S (2018) Health of parents of individuals with developmental disorders or mental health problems: Impacts of stigma. Soc Sci Med 217:152-158
Lorang, Emily; Sterling, Audra; Schroeder, Bianca (2018) Maternal Responsiveness to Gestures in Children With Down Syndrome. Am J Speech Lang Pathol 27:1018-1029
Christensen, Katherine E; Lundwall, Rebecca A (2018) Errors on a computer task and subclinical symptoms of attention-deficit/hyperactivity disorder (ADHD). Scand J Psychol 59:511-517
Travers, Brittany G; Mason, Andrea; Gruben, Kreg G et al. (2018) Standing Balance on Unsteady Surfaces in Children on the Autism Spectrum: The Effects of IQ. Res Autism Spectr Disord 51:9-17
Mahr, Tristan; Edwards, Jan (2018) Using language input and lexical processing to predict vocabulary size. Dev Sci 21:e12685
Weng, Helen Y; Lapate, Regina C; Stodola, Diane E et al. (2018) Visual Attention to Suffering After Compassion Training Is Associated With Decreased Amygdala Responses. Front Psychol 9:771
Dilworth-Bart, Janean E; Poehlmann-Tynan, Julie A; Taub, Amy et al. (2018) Longitudinal associations between self-regulation and the academic and behavioral adjustment of young children born preterm. Early Child Res Q 42:193-204
Heller, Aaron S; Fox, Andrew S; Davidson, Richard J (2018) Parsing affective dynamics to identify risk for mood and anxiety disorders. Emotion :
Goupell, Matthew J; Stoelb, Corey A; Kan, Alan et al. (2018) The Effect of Simulated Interaural Frequency Mismatch on Speech Understanding and Spatial Release From Masking. Ear Hear 39:895-905
Allison, Kristen M; Hustad, Katherine C (2018) Acoustic Predictors of Pediatric Dysarthria in Cerebral Palsy. J Speech Lang Hear Res 61:462-478

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