The UCLA MRRC provides a comprehensive multidisciplinary research program in the field of mental retardation and related aspects of human development. The research activities of the Center are directed towards understanding the basic mechanisms of normal and aberrant.neurobiological development, addressing all of the 20 research priorities listed in the FRA issued by NICHD) for Mental Retardation Research Centers. The long term goals of the Center are to discover ways to prevent mental retardation and to improve the quality of life for mentally retarded and other developmentally disabled individuals. To accomplish this, research is carried out by five organized research groups: Clinical Research, Developmental Biology, Neurobiochemistry, Neurophysiology, and Socio- behavioral studies. The research projects are supported by 6 scientific cores and three general service cores: (l) Molecular Biology, (2) Cell Culture and Microinjection, (3) Neurohistology,. (4) Confocal Microscopy, Qualitative and Quantitative Imaging, (S) Field Work Training, (6) Statistics,(7) Microcomputers/ Media, (8) Technical Services, and (9) Administrative. The function of the Center is to provide an environment promoting the highest level of research in mental retardation at UCLA. The Center will foster interaction among UCLA investigators and facilitate their research through the use of efficient and cost effective core services. The Center assigns high priority to the support of talented young investigators and the training of pre- and postdoctoral fellows in a variety of disciplines related to its goals.

Agency
National Institute of Health (NIH)
Institute
Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD)
Type
Center Core Grants (P30)
Project #
5P30HD004612-27
Application #
2402997
Study Section
Mental Retardation Research Committee (HDMR)
Project Start
1990-08-01
Project End
2000-07-31
Budget Start
1997-08-01
Budget End
1998-07-31
Support Year
27
Fiscal Year
1997
Total Cost
Indirect Cost
Name
University of California Los Angeles
Department
Pediatrics
Type
Other Domestic Higher Education
DUNS #
119132785
City
Los Angeles
State
CA
Country
United States
Zip Code
90095
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Krityakiarana, Warin; Zhao, Paul M; Nguyen, Kevin et al. (2016) Erratum to: Proof-of Concept that an Acute Trophic Factors Intervention After Spinal Cord Injury Provides an Adequate Niche for Neuroprotection, Recruitment of Nestin-Expressing Progenitors and Regeneration. Neurochem Res 41:1844
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Khankan, Rana R; Griffis, Khris G; Haggerty-Skeans, James R et al. (2016) Olfactory Ensheathing Cell Transplantation after a Complete Spinal Cord Transection Mediates Neuroprotective and Immunomodulatory Mechanisms to Facilitate Regeneration. J Neurosci 36:6269-86

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