Abstract

The Imaging Core provides a variety of state-of-the-art digital imaging techniques to MRRC investigators, including three-dimensional volume rendering from optical, electron microscopic, or confocal microscopic images, multi-label fluorescence imaging for localizing cellular molecules, high quality digital light microscopic imaging, high temporal resolution time-lapse confocal imaging, quantitative confocal calcium imaging, and output as high quality print, slides, or digital images. Dr. Scott Pomeroy, formerly the Associate Director, replaced Dr. Kristen Harris, who moved to Boston University in 1999. Dr. Jon Kornhauser has been the Core?s System Manager since 1999. In addition, work-study students assist in the daily administration of the Core facility. The Core occupies 300 square feet of space on two floors of the Enders Building and is supported administratively by Ms. Amy Weinberg.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD)
Type
Center Core Grants (P30)
Project #
2P30HD018655-20
Application #
6501522
Study Section
Project Start
1996-08-01
Project End
2006-06-30
Budget Start
1997-10-01
Budget End
1998-09-30
Support Year
20
Fiscal Year
2001
Total Cost
$86,230
Indirect Cost

  Institution

Name
Children's Hospital Boston
Department
Type
DUNS #
076593722
City
Boston
State
MA
Country
United States
Zip Code
02115

  Publications

Moore, Anna R; Richards, Sarah E; Kenny, Katelyn et al. (2018) Rem2 stabilizes intrinsic excitability and spontaneous firing in visual circuits. Elife 7:
Winawer, Melodie R; Griffin, Nicole G; Samanamud, Jorge et al. (2018) Somatic SLC35A2 variants in the brain are associated with intractable neocortical epilepsy. Ann Neurol 83:1133-1146
Bourassa, Daisy; Elitt, Christopher M; McCallum, Adam M et al. (2018) Chromis-1, a Ratiometric Fluorescent Probe Optimized for Two-Photon Microscopy Reveals Dynamic Changes in Labile Zn(II) in Differentiating Oligodendrocytes. ACS Sens 3:458-467
Leviton, Alan; Joseph, Robert M; Allred, Elizabeth N et al. (2018) Antenatal and Neonatal Antecedents of Executive Dysfunctions in Extremely Preterm Children. J Child Neurol 33:198-208
Hong, Y Kate; Burr, Eliza F; Sanes, Joshua R et al. (2018) Heterogeneity of retinogeniculate axon arbors. Eur J Neurosci :
Chen, Peng; Tao, Liang; Wang, Tianyu et al. (2018) Structural basis for recognition of frizzled proteins by Clostridium difficile toxin B. Science 360:664-669
Anderson, Matthew P (2018) DEPDC5 takes a second hit in familial focal epilepsy. J Clin Invest 128:2194-2196
Fischer, Kathryn D; Houston, Alex C W; Desai, Rajeev I et al. (2018) Behavioral phenotyping and dopamine dynamics in mice with conditional deletion of the glutamate transporter GLT-1 in neurons: resistance to the acute locomotor effects of amphetamine. Psychopharmacology (Berl) 235:1371-1387
Lehrman, Emily K; Wilton, Daniel K; Litvina, Elizabeth Y et al. (2018) CD47 Protects Synapses from Excess Microglia-Mediated Pruning during Development. Neuron 100:120-134.e6
Burnett, Alice C; Anderson, Peter J; Joseph, Robert M et al. (2018) Hand Preference and Cognitive, Motor, and Behavioral Functioning in 10-Year-Old Extremely Preterm Children. J Pediatr 195:279-282.e3

Showing the most recent 10 out of 1442 publications