Abstract

A1. OBJECTIVE The overall objective of the Administrative Core is to facilitate the mission of this IDDRC. Thus, the goals of the Administrative Core are to ensure that 1) research in this Center is focused on problems of relevance and importance to intellectual and developmental disabilities, 2) the research is organized around clearly-defined themes, 3) the research is of the highest scientific quality, 4) there is facilitation of multidisciplinary research and research training, 5) translation of basic research findings to clinical application has high priority, and 6) there is fostering of """"""""centerness"""""""", that leads to synergistic, collaborative interactions between IDDRC investigators. We believe that the activities outlined throughout this grant (see Progress Report, Core Descriptions, and Research Projects Proposed for Core Usage) demonstrate that we are achieving these goals, and it is our intention to build upon our previous successes during the next funding period.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD)
Type
Center Core Grants (P30)
Project #
5P30HD018655-33
Application #
8729881
Study Section
Special Emphasis Panel (ZHD1-DSR-Y)
Project Start
Project End
Budget Start
2014-07-01
Budget End
2015-06-30
Support Year
33
Fiscal Year
2014
Total Cost
$475,056
Indirect Cost
$202,036

  Institution

Name
Children's Hospital Boston
Department
Type
DUNS #
076593722
City
Boston
State
MA
Country
United States
Zip Code
02115

  Publications

Babata, Kikelomo; Bright, H Reeve; Allred, Elizabeth N et al. (2018) Socioemotional dysfunctions at age 10?years in extremely preterm newborns with late-onset bacteremia. Early Hum Dev 121:1-7
Brownstein, Catherine A; Goldstein, Richard D; Thompson, Christopher H et al. (2018) SCN1A variants associated with sudden infant death syndrome. Epilepsia 59:e56-e62
Wong, Man Yan; Liu, Changliang; Wang, Shan Shan H et al. (2018) Liprin-?3 controls vesicle docking and exocytosis at the active zone of hippocampal synapses. Proc Natl Acad Sci U S A 115:2234-2239
Zhang, Sicai; Lebreton, Francois; Mansfield, Michael J et al. (2018) Identification of a Botulinum Neurotoxin-like Toxin in a Commensal Strain of Enterococcus faecium. Cell Host Microbe 23:169-176.e6
Leviton, Alan; Joseph, Robert M; Allred, Elizabeth N et al. (2018) Antenatal and neonatal antecedents of learning limitations in 10-year old children born extremely preterm. Early Hum Dev 118:8-14
Perrin, Eliana M; O'Shea, T Michael; Skinner, Asheley Cockrell et al. (2018) Elevations of inflammatory proteins in neonatal blood are associated with obesity and overweight among 2-year-old children born extremely premature. Pediatr Res 83:1110-1119
Richmond, Camilla A; Rickner, Hannah; Shah, Manasvi S et al. (2018) JAK/STAT-1 Signaling Is Required for Reserve Intestinal Stem Cell Activation during Intestinal Regeneration Following Acute Inflammation. Stem Cell Reports 10:17-26
Leviton, Alan; Hooper, Stephen R; Hunter, Scott J et al. (2018) Antecedents of Screening Positive for Attention Deficit Hyperactivity Disorder in Ten-Year-Old Children Born Extremely Preterm. Pediatr Neurol 81:25-30
Waber, Deborah P; Bryce, Cyralene P; Girard, Jonathan M et al. (2018) Parental history of moderate to severe infantile malnutrition is associated with cognitive deficits in their adult offspring. Nutr Neurosci 21:195-201
Sieker, Jakob T; Proffen, Benedikt L; Waller, Kimberly A et al. (2018) Transcriptional profiling of synovium in a porcine model of early post-traumatic osteoarthritis. J Orthop Res :

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