Abstract

Core D, the Virology/Cancer Core, will provide high level virology and genotyping expertise to the member of the CFAR.
The aims of the Core are as follows: 1. To provide laboratory support for basic AIDS research among CFAR investigators at UNC, Family Health International, and the Research Triangle Institute by providing a high level of expertise in state of the art technologies for culturing and quantitating relevant viruses and for genotyping viral and cellular genomes; 2. To serve as a repository for the short-term and long-term storage of biological specimens (peripheral blood mononuclear cells, plasma, serum, CSF, genital secretions, lymph nodes, etc.) for CFAR investigators; 3. To provide laboratory data to the Clinical/Behavioral Core for CFAR investigators; 4. To train infectious disease and clinical microbiology fellows, and foreign scientists in BSL3 procedures and HIV quantitation techniques.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD)
Type
Center Core Grants (P30)
Project #
5P30HD037260-03
Application #
6354096
Study Section
Project Start
2000-08-01
Project End
2001-07-31
Budget Start
1997-10-01
Budget End
1998-09-30
Support Year
3
Fiscal Year
2000
Total Cost
$244,002
Indirect Cost

  Institution

Name
University of North Carolina Chapel Hill
Department
Type
DUNS #
608195277
City
Chapel Hill
State
NC
Country
United States
Zip Code
27599

  Publications

Wohl, David A; Khan, Maria R; Tisdale, Caroline et al. (2011) Locating the places people meet new sexual partners in a southern US city to inform HIV/STI prevention and testing efforts. AIDS Behav 15:283-91
Cohen, Myron S; Gay, Cynthia L (2010) Treatment to prevent transmission of HIV-1. Clin Infect Dis 50 Suppl 3:S85-95
Anderson, Jeffrey A; Jiang, Hongyu; Ding, Xiao et al. (2008) Genotypic susceptibility scores and HIV type 1 RNA responses in treatment-experienced subjects with HIV type 1 infection. AIDS Res Hum Retroviruses 24:685-94
Edwards, Lloyd J; Stewart, Paul W; MacDougall, James E et al. (2006) A method for fitting regression splines with varying polynomial order in the linear mixed model. Stat Med 25:513-27
Graham, Jinko; McNeney, Brad; Seillier-Moiseiwitsch, Francoise (2005) Stepwise detection of recombination breakpoints in sequence alignments. Bioinformatics 21:589-95
Esther Jr, Charles R; Henry, Marianna M; Molina, Paul L et al. (2005) Nontuberculous mycobacterial infection in young children with cystic fibrosis. Pediatr Pulmonol 40:39-44
Meeker, Rick B; Boles, Jeramiah C; Robertson, Kevin R et al. (2005) Cerebrospinal fluid from human immunodeficiency virus--infected individuals facilitates neurotoxicity by suppressing intracellular calcium recovery. J Neurovirol 11:144-56
Baldewicz, Teri T; Leserman, Jane; Silva, Susan G et al. (2004) Changes in neuropsychological functioning with progression of HIV-1 infection: results of an 8-year longitudinal investigation. AIDS Behav 8:345-55
Thorpe, Joshua M; Smith, Scott R; Trygstad, Troy K (2004) Trends in emergency department antibiotic prescribing for acute respiratory tract infections. Ann Pharmacother 38:928-35
Meeker, R B; Boles, J C; Bragg, D C et al. (2004) Development of neuronal sensitivity to toxins in cerebrospinal fluid from HIV-type 1-infected individuals. AIDS Res Hum Retroviruses 20:1072-86

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