01. OBJECTIVES The Translational Neuroimaging (TNI) Core provides IDDRC investigators access to state of the art in vivo multimodality whole organism imaging from mouse to man, with special facilities to accommodate pediatric subjects. In addition to state of the art hardware, software and applications, this Core provides essential collaborative human resources to support the design, implementation, and acquisition and analysis phases of neuroimaging investigation. As such, the TNI core is one arm of a comprehensive effort by multiple IDDRC Cores to develop a broad, deep and accessible repository of human and animal data relating to normal development and disease states. The focal point of this core is the Gruss Magnetic Resonance Research Center (MRRC), which houses 9.4 Tesla small animal and 3.0 Tesla human MRI systems, with extensive support facilities.

Agency
National Institute of Health (NIH)
Institute
Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD)
Type
Center Core Grants (P30)
Project #
5P30HD071593-04
Application #
8734923
Study Section
Special Emphasis Panel (ZHD1-DSR-Y)
Project Start
Project End
Budget Start
2014-07-01
Budget End
2015-06-30
Support Year
4
Fiscal Year
2014
Total Cost
$128,585
Indirect Cost
$51,587
Name
Albert Einstein College of Medicine
Department
Type
DUNS #
110521739
City
Bronx
State
NY
Country
United States
Zip Code
10461
Saied-Santiago, Kristian; Bülow, Hannes E (2018) Diverse roles for glycosaminoglycans in neural patterning. Dev Dyn 247:54-74
Wang, Ping; Zhao, Dejian; Lachman, Herbert M et al. (2018) Enriched expression of genes associated with autism spectrum disorders in human inhibitory neurons. Transl Psychiatry 8:13
Zhao, Yingjie; Guo, Tingwei; Fiksinski, Ania et al. (2018) Variance of IQ is partially dependent on deletion type among 1,427 22q11.2 deletion syndrome subjects. Am J Med Genet A 176:2172-2181
Boudewyn, Lauren C; Walkley, Steven U (2018) Current concepts in the neuropathogenesis of mucolipidosis type IV. J Neurochem :
Wilson, Tommy J; Gray, Michael J; Van Klinken, Jan-Willem et al. (2018) Macronutrient composition of a morning meal and the maintenance of attention throughout the morning. Nutr Neurosci 21:729-743
Barnes, Jesse; Salas, Franklin; Mokhtari, Ryan et al. (2018) Modeling the neuropsychiatric manifestations of Lowe syndrome using induced pluripotent stem cells: defective F-actin polymerization and WAVE-1 expression in neuronal cells. Mol Autism 9:44
Celestrin, Kevin; Díaz-Balzac, Carlos A; Tang, Leo T H et al. (2018) Four specific immunoglobulin domains in UNC-52/Perlecan function with NID-1/Nidogen during dendrite morphogenesis in Caenorhabditis elegans. Development 145:
Thomsen, Anna M; Gulinello, Maria E; Wen, Jing et al. (2018) Liposomal Cytarabine Induces Less Neurocognitive Dysfunction Than Intrathecal Methotrexate in an Animal Model. J Pediatr Hematol Oncol 40:e91-e96
Pera, Marta; Larrea, Delfina; Guardia-Laguarta, Cristina et al. (2017) Increased localization of APP-C99 in mitochondria-associated ER membranes causes mitochondrial dysfunction in Alzheimer disease. EMBO J 36:3356-3371
Boudewyn, Lauren C; Sikora, Jakub; Kuchar, Ladislav et al. (2017) N-butyldeoxynojirimycin delays motor deficits, cerebellar microgliosis, and Purkinje cell loss in a mouse model of mucolipidosis type IV. Neurobiol Dis 105:257-270

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