The Bio-Behavioral Core will advance high-impact, integrated biomedical, behavioral, and social science research in HIV prevention and care from conceptualization to proposal submission and from data collection to interpretation and dissemination. Although effective combination antiretroviral therapy (ART) can reduce HIV transmission, new infections continue to occur, and diagnoses surpass deaths each year. Every biomedical strategy for preventing and treating HIV infection (e.g., ART, PrEP, PEP, intravaginal rings, condoms, microbicides, and future vaccines and broadly neutralizing monoclonal antibodies] has behavioral components that influence efficacy and effectiveness. Unless biomedical strategies are acceptable, widely disseminated, and adhered to and take into consideration co-morbidities such as mental health and substance use and health and social disparities, their impact on the AIDS epidemic will be limited. The Bio-Behavioral Core will provide a comprehensive approach that integrates biomedical, behavioral and social science, and clinical perspectives for HIV prevention and treatment research, using Syndemics Theory as a guiding framework for advancing bio- behavioral research. The Core has three Specific Aims: (1) to stimulate high-impact bio-behavioral research on emerging priority topics at the interface of biomedical and behavioral science; (2) to provide expertise on selection of biological measures, sample collection and assay, and interpretation of resulting data; and (3) to prioritize clinical perspectives through partnerships with HIV and non-HIV care providers. The Bio-Behavioral Core will accomplish its Aims through a range of functions that include expert consultation to HIV Center researchers on research design, intervention development, biomarkers, social science theories, and research partnerships with providers; Scientific Working Groups, integrated diverse teams of biomedical, clinical, and social science researchers who come together to develop competitive research proposals that meet the most pressing clinical, scientific, and policy challenges; and annual Symposia that bring preeminent researchers to the HIV Center for intensive exploration of selected pressing scientific dilemmas to stimulate new scientific questions and, ultimately, multidisciplinary research grant proposals. We will identify shared scientific goals that bridge disciplinary silos; build collaborative interdisciplinary teams to address these goals; and support an integrated bio-behavioral research agenda. The Core Director will be Laurie Bauman, Ph.D., a sociologist, Professor of Pediatrics, and Director of the Prevention Intervention Research Center at the Albert Einstein College of Medicine. Core Co-Director, Michael Yin, M.D., is an Associate Professor of Medicine at Columbia University who manages care for PLWH, provides PrEP-related services, and is an investigator in the CUMC AIDS Clinical Trials Group (ACTG). Through the strengths of its Members and Affiliates in behavioral, social, and biomedical sciences and clinical research and care, the Bio- Behavioral Core will provide essential infrastructure to support a Center-wide learning community.

Agency
National Institute of Health (NIH)
Institute
National Institute of Mental Health (NIMH)
Type
Center Core Grants (P30)
Project #
5P30MH043520-33
Application #
10090640
Study Section
Special Emphasis Panel (ZMH1)
Project Start
1987-09-30
Project End
2023-01-31
Budget Start
2021-02-01
Budget End
2022-01-31
Support Year
33
Fiscal Year
2021
Total Cost
Indirect Cost
Name
New York State Psychiatric Institute
Department
Type
DUNS #
167204994
City
New York
State
NY
Country
United States
Zip Code
10032
Parcesepe, Angela M; Tymejczyk, Olga; Remien, Robert et al. (2018) Household decision-making power and the mental health and well-being of women initiating antiretroviral treatment in Oromia, Ethiopia. AIDS Care 30:211-218
Pathela, Preeti; Jamison, Kelly; Braunstein, Sarah L et al. (2018) Gaps Along the HIV Care Continuum: Findings Among a Population Seeking Sexual Health Care Services in New York City. J Acquir Immune Defic Syndr 78:314-321
Philbin, Morgan M; Flake, Morgan; Hatzenbuehler, Mark L et al. (2018) State-level immigration and immigrant-focused policies as drivers of Latino health disparities in the United States. Soc Sci Med 199:29-38
Rael, Christine Tagliaferri; Martinez, Michelle; Giguere, Rebecca et al. (2018) Barriers and Facilitators to Oral PrEP Use Among Transgender Women in New York City. AIDS Behav 22:3627-3636
Mbote, David Kuria; Sandfort, Theo G M; Waweru, Esther et al. (2018) Kenyan Religious Leaders' Views on Same-Sex Sexuality and Gender Nonconformity: Religious Freedom versus Constitutional Rights. J Sex Res 55:630-641
Sandfort, Theo G M; Bos, Henny; Reddy, Vasu (2018) Gender Expression and Mental Health in Black South African Men Who Have Sex with Men: Further Explorations of Unexpected Findings. Arch Sex Behav 47:2481-2490
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Giguere, Rebecca; Rael, Christine Tagliaferri; Sheinfil, Alan et al. (2018) Factors Supporting and Hindering Adherence to Rectal Microbicide Gel Use with Receptive Anal Intercourse in a Phase 2 Trial. AIDS Behav 22:388-401
Nestadt, Danielle Friedman; Lakhonpon, Sudrak; Pardo, Gisselle et al. (2018) A Qualitative Exploration of Psychosocial Challenges of Perinatally HIV-Infected Adolescents and Families in Bangkok, Thailand. Vulnerable Child Youth Stud 13:158-169
Levine, Ethan Czuy; Martinez, Omar; Mattera, Brian et al. (2018) Child Sexual Abuse and Adult Mental Health, Sexual Risk Behaviors, and Drinking Patterns Among Latino Men Who Have Sex With Men. J Child Sex Abus 27:237-253

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