The Laboratory for the Study of Behavioral Processes is dedicated to elucidating the associations of physical and mental health problems with everyday behavioral and emotional functioning. Previous activities of this lab have made important substantive and methodological contributions to the study of mental health in older people. Currently proposed activities will continue and extend those activities in keeping with the focus of the CRC on efficacy and effectiveness of interventions to treat and prevent mental disorders among older persons with co-morbid health problems.
Specific aims of the Behavioral Processes Lab are: (1) to characterize the effective and behavioral concomitants of depression and other mental disorders among older persons with co-morbid medical illness, including dementia; (2) to identify affective and behavioral predictors of the development, course, and responsivity including dementia; (2) to identify affective and behavioral predictors of the development, course, and responsivity to treatment of late life mental disorders; (3) to develop and validate innovate behavioral methods for prevention and treatment of late life mental disorders, and (4) to develop and validate innovate methods and measures for evaluating the efficacy and the effectiveness of such interventions. The Behavioral Processes Laboratory will achieve these aims primarily through a series of focused research projects examining psychological, behavioral, and interpersonal processes associated with physical and mental health in late life. These studies focus on diverse populations, measures, and methods, but all deal with intrapersonal and interpersonal processes, leading to, or resulting from depressive illness among physically frail older persons. Specific projects proposed for this funding period include: (1) development and implementation of an intervention to facilitate adaptation to long-term residential care; (2) pilot research on everyday social support and quality of life during and following chemotherapy for breast cancer; (3) development and implementation of a treatment protocol for conducting psychotherapy with depressed older persons with dementia; (4) examination of coping and adaptation in end-stage renal disease, and (5) interrelated studies of daily interactions between two populations of chronically ill individuals and their family caregivers: Persons with AIDS of all ages, and cognitively intact, chronically ill older persons.

Agency
National Institute of Health (NIH)
Institute
National Institute of Mental Health (NIMH)
Type
Center Core Grants (P30)
Project #
3P30MH052129-07S2
Application #
6595033
Study Section
Project Start
2000-09-01
Project End
2002-08-31
Budget Start
Budget End
Support Year
7
Fiscal Year
2002
Total Cost
$262,244
Indirect Cost
Name
University of Pennsylvania
Department
Type
DUNS #
042250712
City
Philadelphia
State
PA
Country
United States
Zip Code
19104
Gallo, Joseph J; Morales, Knashawn H; Bogner, Hillary R et al. (2013) Long term effect of depression care management on mortality in older adults: follow-up of cluster randomized clinical trial in primary care. BMJ 346:f2570
Wallace, Meredith L; Dombrovski, Alexandre Y; Morse, Jennifer Q et al. (2012) Coping with health stresses and remission from late-life depression in primary care: a two-year prospective study. Int J Geriatr Psychiatry 27:178-86
Joo, Jin Hui; Morales, Knashawn H; de Vries, Heather F et al. (2010) Disparity in use of psychotherapy offered in primary care between older african-american and white adults: results from a practice-based depression intervention trial. J Am Geriatr Soc 58:154-60
Wallace, Meredith L; Anderson, Stewart J; Mazumdar, Sati (2010) A stochastic multiple imputation algorithm for missing covariate data in tree-structured survival analysis. Stat Med 29:3004-16
Raue, Patrick J; Morales, Knashawn H; Post, Edward P et al. (2010) The wish to die and 5-year mortality in elderly primary care patients. Am J Geriatr Psychiatry 18:341-50
Gopalakrishnan, Raman; Ross, Jennifer; O'Brien, Charles et al. (2009) Course of late-life depression with alcoholism following combination therapy. J Stud Alcohol Drugs 70:237-41
Alexopoulos, George S; Reynolds 3rd, Charles F; Bruce, Martha L et al. (2009) Reducing suicidal ideation and depression in older primary care patients: 24-month outcomes of the PROSPECT study. Am J Psychiatry 166:882-90
Murphy, Susan A; Lynch, Kevin G; Oslin, David et al. (2007) Developing adaptive treatment strategies in substance abuse research. Drug Alcohol Depend 88 Suppl 2:S24-30
Gallo, Joseph J; Bogner, Hillary R; Morales, Knashawn H et al. (2007) The effect of a primary care practice-based depression intervention on mortality in older adults: a randomized trial. Ann Intern Med 146:689-98
Bogner, Hillary R; Bruce, Martha L; Reynolds 3rd, Charles F et al. (2007) The effects of memory, attention, and executive dysfunction on outcomes of depression in a primary care intervention trial: the PROSPECT study. Int J Geriatr Psychiatry 22:922-9

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