This application requests core support (P30) to establish a Center for Early Detection, Prevention, and Treatment of HIV (ED-PaTH) in Los Angeles (LA) LA is the second largest AIDS epicenter in the U.S.; its population is highly diverse; and the county is spread over 419 miles. Researchers, community members, service providers, and governmental agencies need to be linked in LA; therefore, an interdisciplinary group (43% minority investigators) has formed a Center in order to enhance understanding of emerging scientific breakthroughs in HIV research and to promote early detection, effective prevention, and treatment programs for HIV at the societal, community, and individual levels. To accomplish this mission, four Cores will support the design, implementation, and evaluation of existing funded projects and assist in the development of new research protocols focused on communities, systems-of-care, service providers, and individuals at risk. Specifically, in the areas of early HIV detection, prevention, and treatment, we will have: (1) an Administrative Core to identify strategies for addressing policy issues related to emerging new technologies and findings by coordinating examination of issues in their broader contexts within multi-layered, multi-disciplinary teams; (2) an Assessment Core to develop multi- method reliable and valid assessment measures that integrate biological and psychosocial indices and that are sensitive to ethnic, gender, and socioeconomic influences; 3) an Intervention Core to examine the theories, designs, delivery, and quality of HIV-related services and dissemination of successful programs; and (4) an Evaluation Core to develop innovative biostatistical analytic strategies, assist community-based program evaluation, and enhance our understanding of cost-effectiveness. These Cores will enhance researchers' and the communities' awareness, skills, resources, and capacities to generate high quality HIV research and training. Each Core will deliver consultation, technical assistance, enhance communication within their area of expertise, and participate in training activities. The broader HIV community in LA will benefit from the following aspects of the Center a strategic planning process involving researcher-community partners, an Annual Policy Forum, routine updates and bibliographic support, consultation from the Cores, colloquia, the existence of an infrastructure to foster collaborations and improve the quality of our science, and increased training opportunities for faculty and students interested in the area of HIV. The Center, aimed primarily at social and behavioral HIV research, is proposed, anticipating a complementary application for a Center for AIDS Research (CFAR) that focuses on clinical and basic science HIV-related research.

Agency
National Institute of Health (NIH)
Institute
National Institute of Mental Health (NIMH)
Type
Center Core Grants (P30)
Project #
5P30MH058107-03
Application #
2891075
Study Section
Special Emphasis Panel (ZMH1-BRB-D (04))
Program Officer
Rausch, Dianne M
Project Start
1997-09-30
Project End
2002-08-31
Budget Start
1999-09-30
Budget End
2000-08-31
Support Year
3
Fiscal Year
1999
Total Cost
Indirect Cost
Name
University of California Los Angeles
Department
Type
Other Domestic Higher Education
DUNS #
119132785
City
Los Angeles
State
CA
Country
United States
Zip Code
90095
Bristow, Claire C; Klausner, Jeffrey D (2018) Using Treponemal Assay Signal Strength Cutoff Ratios To Predict Syphilis Infection. J Clin Microbiol 56:
Beymer, Matthew R; Kofron, Ryan M; Tseng, Chi-Hong et al. (2018) Results from the post-exposure prophylaxis pilot program (P-QUAD) demonstration project in Los Angeles County. Int J STD AIDS 29:557-562
Zhao, Yan; Wu, Zunyou; McGoogan, Jennifer M et al. (2018) Nationwide cohort study of antiretroviral therapy timing: treatment dropout and virological failure in China, 2011-2015. Clin Infect Dis :
Refugio, Oliver N; Klausner, Jeffrey D (2018) Syphilis incidence in men who have sex with men with human immunodeficiency virus comorbidity and the importance of integrating sexually transmitted infection prevention into HIV care. Expert Rev Anti Infect Ther 16:321-331
Braun, Hannan M; Segura, Eddy R; Lake, Jordan E et al. (2018) Individual and partnership factors associated with anticipated versus actual partner notification following STI diagnosis among men who have sex with men and/or with transgender women in Lima, Peru. Sex Transm Infect 94:607-610
DeVost, Michelle A; Beymer, Matthew R; Weiss, Robert E et al. (2018) App-Based Sexual Partner Seeking and Sexually Transmitted Infection Outcomes: A Cross-Sectional Study of HIV-Negative Men Who Have Sex With Men Attending a Sexually Transmitted Infection Clinic in Los Angeles, California. Sex Transm Dis 45:394-399
Dangerfield 2nd, Derek T; Harawa, Nina T; Fernandez, M Isabel et al. (2018) Age Cohort Differences in Sexual Behaviors Among Black Men Who Have Sex With Men and Women. J Sex Res 55:1012-1021
Dangerfield, Derek T; Harawa, Nina T; McWells, Charles et al. (2018) Exploring the preferences of a culturally congruent, peer-based HIV prevention intervention for black men who have sex with men. Sex Health :
Aralis, Hilary J; Shoptaw, Steve; Brookmeyer, Ron et al. (2018) Psychiatric Illness, Substance Use, and Viral Suppression Among HIV-Positive Men of Color Who Have Sex with Men in Los Angeles. AIDS Behav 22:3117-3129
Bristow, Claire C; Shannon, Chelsea; Herbst de Cortina, Sasha et al. (2018) Use of Oral Fluid With a Rapid Treponemal Test for Syphilis Evaluation. Sex Transm Dis 45:e65-e67

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