The Methods Core provides expertise, leadership and infrastructure to promote and facilitate the quality of HIV research conducted by CHIPTS researchers and collaborators, both domestically and globally. The Methods Core has a history of venturing to the cutting edge of research methodology and technology to offer the HIV research community new platforms and tools to optimize the potential of their research. This includes integrating mobile phone-based assessment, biomarker data, and other measurement techniques into study designs that maintain scientific rigor while adapting to the evolving environment of HIV prevention research. Consistent with OAR's NIH HIV/AIDS funding priorities, the Methods Core will provide services to guide research linked to HIV, with specific focus on comorbidities of substance use and mental health disorders that interfere with consistent viral suppression in HIV-positive individuals and in sustaining optimal prophylaxis for high-risk individuals. The Methods Core recognizes the paradigm shift required beyond traditional analytic approaches to incorporate advanced analytical approaches, and to broaden involvement across different disciplines, such as medicine, HIV, mental health and drug abuse research fields. As well, the interplay of technology and implementation science requires method development to advise HIV intervention delivery in real-world settings. Its three specific aims are: (1) SCIENCE: To foster cutting edge research by developing and disseminating innovative technologies and analytic strategies (e.g., modern measurement tools and multivariate statistical techniques) to HIV treatment and prevention research; (2) NETWORKING: To connect scientists across disciplines and with community partners to understand the available analytic methodologies and linking scientists to partners with complementary expertise; and (3) CAPACITY BUILDING: To recruit, mentor, retain high caliber investigators with methods expertise and to disseminate innovative methods, tools, and platforms through seminars and webinars. The Methods Core is a backbone for both CHIPTS scientists and community partners and prioritizes three overlapping areas of focus when providing services: measurement, statistical methods and multivariate models, and implementation science. The Methods Core is led by Director Li Li, PhD, Co-Director W Scott Comulada, DrPH, and Associate Director Sung Jae-Lee, PhD. The types of services provided include consultations on research design, power and sample-size calculations, data analysis, data management, grant proposal development, preparation of research findings for publication, training workshops and seminars and selection of appropriate models, including analysis of multiple biomedical and behavioral HIV end points. Epidemiological and biostatistical expertise within a broader causal-inference paradigm have always been central to guiding services provided by the Methods Core.

National Institute of Health (NIH)
National Institute of Mental Health (NIMH)
Center Core Grants (P30)
Project #
Application #
Study Section
Special Emphasis Panel (ZMH1)
Project Start
Project End
Budget Start
Budget End
Support Year
Fiscal Year
Total Cost
Indirect Cost
University of California Los Angeles
Los Angeles
United States
Zip Code
Li, Michael J; Okafor, Chukwuemeka N; Gorbach, Pamina M et al. (2018) Intersecting burdens: Homophobic victimization, unstable housing, and methamphetamine use in a cohort of men of color who have sex with men. Drug Alcohol Depend 192:179-185
Ojikutu, Bisola O; Bogart, Laura M; Higgins-Biddle, Molly et al. (2018) Facilitators and Barriers to Pre-Exposure Prophylaxis (PrEP) Use Among Black Individuals in the United States: Results from the National Survey on HIV in the Black Community (NSHBC). AIDS Behav 22:3576-3587
Reback, Cathy J; Fletcher, Jesse B (2018) Elevated HIV and STI Prevalence and Incidence Among Methamphetamine-Using Men Who Have Sex With Men in Los Angeles County. AIDS Educ Prev 30:350-356
Kojima, Noah; Klausner, Jeffrey D (2018) An Update on the Global Epidemiology of Syphilis. Curr Epidemiol Rep 5:24-38
Panagiotoglou, D; Olding, M; Enns, B et al. (2018) Building the Case for Localized Approaches to HIV: Structural Conditions and Health System Capacity to Address the HIV/AIDS Epidemic in Six US Cities. AIDS Behav 22:3071-3082
Pines, Heather A; Semple, Shirley J; Strathdee, Steffanie A et al. (2018) Vaginal washing and lubrication among female sex workers in the Mexico-US border region: implications for the development of vaginal PrEP for HIV prevention. BMC Public Health 18:1009
Montgomery, Tiffany M; Mays, Vickie M; Heilemann, MarySue V et al. (2018) Acceptability and Feasibility of a Sexual Health Intervention for Young Adult Black Women. J Obstet Gynecol Neonatal Nurs 47:862-873
Javanbakht, Marjan; Westmoreland, Drew; Gorbach, Pamina (2018) Factors Associated With Pharyngeal Gonorrhea in Young People: Implications for Prevention. Sex Transm Dis 45:588-593
Lan, Chiao-Wen; Lin, Chunqing; Thanh, Duong Cong et al. (2018) Drug-related stigma and access to care among people who inject drugs in Vietnam. Drug Alcohol Rev 37:333-339
Li, Li; Hien, Nguyen Tran; Liang, Li-Jung et al. (2018) Efficacy of Communication Training of Community Health Workers on Service Delivery to People Who Inject Drugs in Vietnam: A Clustered Randomized Trial. Am J Public Health 108:791-798

Showing the most recent 10 out of 715 publications