Abstract

The goal of the Immunocytopathology Core is primarily one of providing access to surgical pathology specimens as well as providing molecular support. Specific services include: 1. Procurement and Delivery 2. Immunophenotyping 3. In situ hybridization 4. Histochemical special strains 5. In situ PCR The Director of the Core will additionally work with individual CFAR investigators to provide possible strategies for improving our ability to answer a number of important questions relating to HIV.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Mental Health (NIMH)
Type
Center Core Grants (P30)
Project #
3P30MH059037-14S1
Application #
6507452
Study Section
Project Start
2001-05-10
Project End
2003-02-28
Budget Start
1997-10-01
Budget End
1998-09-30
Support Year
14
Fiscal Year
2001
Total Cost
$165,355
Indirect Cost

  Institution

Name
University of California San Francisco
Department
Type
DUNS #
073133571
City
San Francisco
State
CA
Country
United States
Zip Code
94143

  Publications

Josefsson, Lina; von Stockenstrom, Susanne; Faria, Nuno R et al. (2013) The HIV-1 reservoir in eight patients on long-term suppressive antiretroviral therapy is stable with few genetic changes over time. Proc Natl Acad Sci U S A 110:E4987-96
Josefsson, Lina; Eriksson, Susanne; Sinclair, Elizabeth et al. (2012) Hematopoietic precursor cells isolated from patients on long-term suppressive HIV therapy did not contain HIV-1 DNA. J Infect Dis 206:28-34
Papasavvas, Emmanouil; Hsue, Priscilla; Reynolds, Griffin et al. (2012) Increased CD34+/KDR+ cells are not associated with carotid artery intima-media thickness progression in chronic HIV-positive subjects. Antivir Ther 17:557-63
Hunt, Peter W; Landay, Alan L; Sinclair, Elizabeth et al. (2011) A low T regulatory cell response may contribute to both viral control and generalized immune activation in HIV controllers. PLoS One 6:e15924
Hunt, Peter W; Hatano, Hiroyu; Sinclair, Elizabeth et al. (2011) HIV-specific CD4+ T cells may contribute to viral persistence in HIV controllers. Clin Infect Dis 52:681-7
Hunt, Peter W; Cao, Huyen L; Muzoora, Conrad et al. (2011) Impact of CD8+ T-cell activation on CD4+ T-cell recovery and mortality in HIV-infected Ugandans initiating antiretroviral therapy. AIDS 25:2123-31
Kitchen, Christina M R; Yeghiazarian, Lilit; Hoh, Rebecca et al. (2011) Immune activation, CD4+ T cell counts, and viremia exhibit oscillatory patterns over time in patients with highly resistant HIV infection. PLoS One 6:e21190
Favre, David; Stoddart, Cheryl A; Emu, Brinda et al. (2011) HIV disease progression correlates with the generation of dysfunctional naive CD8(low) T cells. Blood 117:2189-99
Hunt, Peter W; Martin, Jeffrey N; Sinclair, Elizabeth et al. (2011) Valganciclovir reduces T cell activation in HIV-infected individuals with incomplete CD4+ T cell recovery on antiretroviral therapy. J Infect Dis 203:1474-83
Favre, David; Mold, Jeff; Hunt, Peter W et al. (2010) Tryptophan catabolism by indoleamine 2,3-dioxygenase 1 alters the balance of TH17 to regulatory T cells in HIV disease. Sci Transl Med 2:32ra36

Showing the most recent 10 out of 157 publications