The Clinical Assessment Core provides a range of services to Center investigators related to clinical assessments. Specifically, the Clinical Assessment Core will: (1) provide to PMHARC-related studies clinical and self-report behavioral assessments administered by highly trained core personnel; (2) provide diagnostician recruitment, training, and ongoing calibration in order to maintain high quality; (3) oversee the administration of a core battery in all Center pilot treatment studies and (where possible) R01s that includes the Risk Assessment Battery, Quick Inventory of Depressive Symptoms, the BASIS-24, and SF-12; (4) provide consultation on a broad range of behavioral, neuropsychological, and medication adherence measures to PMHARC investigators. By providing a shared diagnostic assessment resource, the Clinical Assessment Core maximizes the quality of assessments and minimizes cost for all Center investigators (diagnostic assessments are provided to PMHARC pilot studies at no cost to the investigator). By administering the same core battery measures across all studies, the Core is able to compile a pooled database with substantially larger sample sizes. This larger database enables Center investigators to ask broader questions about the interactions of psychiatric status and HIV disease status and examine subpopulations stratified by gender, race, and ethnicity. The Clinical Assessment Core will continuously monitor and regularly evaluate each of the services that it will provide. Summary of the feedback from investigators will be given to the Center Executive Committee, Internal Advisory Board, and External Advisory Committee for comments and suggestions. The Clinical Assessment Core will be directed by Paul Crits-Christoph, who has extensive experience as an NIH Center Director and in the assessment of patients for psychiatric studies, and co- directed by Robert Gross, who has extensive experience in the treatment of patients with HIV/AIDS and in assessing adherence to medications, and Cobb Scott, who is experienced in the neuropsychological assessment of HIV+ patients.

National Institute of Health (NIH)
National Institute of Mental Health (NIMH)
Center Core Grants (P30)
Project #
Application #
Study Section
Special Emphasis Panel (ZMH1)
Project Start
Project End
Budget Start
Budget End
Support Year
Fiscal Year
Total Cost
Indirect Cost
University of Pennsylvania
United States
Zip Code
Crits-Christoph, Paul; Gallop, Robert; Noll, Elizabeth et al. (2018) Impact of a medical home model on costs and utilization among comorbid HIV-positive Medicaid patients. Am J Manag Care 24:368-375
Merlin, Jessica S; Long, Dustin; Becker, William C et al. (2018) Brief Report: The Association of Chronic Pain and Long-Term Opioid Therapy With HIV Treatment Outcomes. J Acquir Immune Defic Syndr 79:77-82
Momplaisir, Florence M; Aaron, Erika; Bossert, Lisa et al. (2018) HIV care continuum outcomes of pregnant women living with HIV with and without depression. AIDS Care 30:1580-1585
Vujkovic, Marijana; Bellamy, Scarlett L; Zuppa, Athena F et al. (2018) Polymorphisms in cytochrome P450 are associated with extensive efavirenz pharmacokinetics and CNS toxicities in an HIV cohort in Botswana. Pharmacogenomics J 18:678-688
Coviello, D M; Lovato, R; Apostol, K et al. (2018) Prevalence of HIV Viral Load Suppression Among Psychiatric Inpatients with Comorbid Substance Use Disorders. Community Ment Health J :
Wood, Sarah; Ratcliffe, Sarah; Gowda, Charitha et al. (2018) Impact of insurance coverage on HIV transmission potential among antiretroviral therapy-treated youth living with HIV. AIDS 32:895-902
Hill, David A; Lim, Hee-Woong; Kim, Yong Hoon et al. (2018) Distinct macrophage populations direct inflammatory versus physiological changes in adipose tissue. Proc Natl Acad Sci U S A 115:E5096-E5105
Opondo, Philip R; Ho-Foster, Ari R; Ayugi, James et al. (2018) HIV Prevalence Among Hospitalized Patients at the Main Psychiatric Referral Hospital in Botswana. AIDS Behav 22:1503-1516
Schnoll, Robert A; Thompson, Morgan; Serrano, Katrina et al. (2018) Rate of Nicotine Metabolism and Tobacco Use among Persons with HIV: Implications for Treatment and Research. J Acquir Immune Defic Syndr :
Torgersen, Jessie; Bellamy, Scarlett L; Ratshaa, Bakgaki et al. (2018) Impact of Efavirenz Metabolism on Loss to Care in Older HIV+ Africans. Eur J Drug Metab Pharmacokinet :

Showing the most recent 10 out of 74 publications